mardi 25 septembre 2018

Onco Actu du 25 septembre 2018

3.1.1 Prévention - Tabac - e-cigs

Potential Benefits and Risks of High-Nicotine e-Cigarettes [JAMA]

Special Report: High-nicotine e-cigarettes flood market despite FDA rule [Reuters]

4.12 Biopsies liquides

Foundation, Roche launch new 70-gene cancer blood test following June buyout [FierceBiotech]

4.5 Dép., diag. & prono. - Colorectal

Colorectal cancer screening: Science should trump convenience [STAT]

5.10 Traitements - Essais

Clinical trial investigators violate EU regulations: Entries in EU Register are incomplete [IQWIG]

5.12 Immunothérapies

Cancer cells evade immunotherapy by hiding telltale marker, suggesting how to stop relapse [Fred Hutch]

5.12.6 Immunothérapies - AMM

BLINCYTO® (blinatumomab) Approved In Japan For The Treatment Of Relapsed Or Refractory B-cell Acute Lymphoblastic Leukemia [Amgen]

European Commission approves Imfinzi for locally-advanced, unresectable NSCLC [AstraZeneca]

EU approves AstraZeneca immunotherapy drug for lung cancer [Reuters]

5.13 WCLC

IMpower132 Study Shows Atezolizumab in Combination With Carboplatin and Pemetrexed Reduced the Risk of Disease Worsening or Death (PFS) in Stage IV Non-Squamous NSCLC [IASLC]

Study Demonstrates Reliability of Trained Dogs in the Identification of Malignant Pulmonary Nodules [IASLC]

Roche Left Seeking a Niche as Merck Dominates Lung-Cancer Market [Bloomberg]

Smoking Cessation Services Widely Accepted During Lung Cancer Screenings [IASLC]

Women With Non-Small Cell Lung Cancers Live Longer Than Men, WCLC Study Shows [IASLC]

Roche’s Tecentriq in combination with pemetrexed and platinum-based chemotherapy reduced the risk of disease worsening or death in a type of previously untreated advanced lung cancer [Roche]

Opening Plenary Speaker at World Conference on Lung Cancer Examines How Serious Illness Can Create Important Sense of Meaning for HCPs, Caregivers and Patients [IASLC]

Study Shows Outdoor Air Pollution Exposure Significantly Higher in Women Non-Smokers With Lung Cancer Than Women Smokers With Lung Cancer [IASLC]

Roche’s investigational medicine entrectinib showed a durable response of more than two years in people with a specific type of lung cancer [Roche]

5.2 Pharma

FDA lifts hold on Epizyme cancer drug, shares surge [FierceBiotech]

Another Precision Step for Roche as Ignyta Drug Heads to Regulators [Xconomy]

5.3 Traitements - FDA, EMA, NICE...

Companies stepping up efforts to ensure medicine supply post Brexit [EMA]

5.3.4 Traitements - AMM (FDA, EMA,...)

Verastem Oncology Receives FDA Approval of COPIKTRA™ (duvelisib) Capsules [Verastem]

Unwanted by AbbVie and Infinity, battered Verastem gets an OK for duvelisib and a second shot at success [EndPoints]

5.5 ASCO

Three Studies Reveal Cancer Patients Face Serious Financial Hardship, Do Not Discuss Treatment Costs With Physicians [ASCO]

6. Lutte contre les cancers

Hope and Challenge: The NCI Annual Plan and Budget Proposal for Fiscal Year 2020 [NCI]

6.5 Médecines alternatives/complémentaires

How online crowdfunding supports cancer quacks [Respectful Insolence]

6.8 Communication

Cancer In The News: Bias And Quality In Media Reporting Of Cancer Research. [bioRxiv]

6.9 Controverses

Scientific Advocacy and Biases of the Ideological and Industry Kinds [Absolutely Maybe]