mardi 18 septembre 2018

Onco Actu du 18 septembre 2018

1.1 Biologie - Gènes

Scientists dig up cancer’s secrets buried in ‘gene deserts’ [Institute of Cancer Research]

2. Etiologie

High levels of fertility-related hormone linked to increased breast cancer risk, new study finds [Institute of Cancer Research]

2.10 Etiologie - Alcool

In response to critic, NIH alcoholism institute changes online explanation of cancer risk from drinking [STAT]

3.1.1 Prévention - Tabac - e-cigs

Gottlieb to E-Cigarette Manufacturers: Reduce Youth Use or I Will END You [FDA Law Blog]

3.4.1 Chimioprévention - aspirine

Too soon to draw conclusions from new data finding no health benefit to aspirin [ACS]

4. Dépistage, diagnostic et pronostic

Pathology staff shortages causing delays to cancer diagnosis, says report [Cancer Research UK]

NCI and FDA Address Common Concerns: A Win–Win for Making Progress against Cancer [NCI]

4.12 Biopsies liquides

New blood test detects early stage pancreatic cancer [Lund University]

4.2 Dép., diag. & prono. - Génome

Many cancer patients' relatives might get gene tests if price is right [Reuters]

The BRCA1 Gene: Trouble, Quantified [In the Pipeline]

5.12.2 Immunothérapies - CAR-T, thérapies cellulaires

London biotherapeutics powerhouse launched by Cancer Research UK [Cancer Research UK]

Cancer Research UK launches new London Centre, infusing £14M into biotherapeutics work from leading institutes [EndPoints]

5.2 Pharma

FDA lifts clinical hold from Mersana’s breast cancer trial [FierceBiotech]

Mersana Announces FDA Lifts Partial Clinical Hold for XMT-1522 [Mersana]

Mersana gets a boost as FDA offers a quick thumbs-up for its clinical plan to lift a partial hold [EndPoints]

5.4 Traitements - Economie

Patients with high-risk skin cancer have new treatment option [NICE]

Targeted treatment for melanoma to be free on NHS [BBC News]

6.1 Observation

Risk of Developing Endocrinopathy Determined in Children and Young Adults after Radiotherapy for Brain Tumours [ESMO]

6.11 Patients

Siblings affected by childhood cancer: ‘It’s one of those moments when time kind of stands still’ – Meg and Beth’s story [Cancer Research UK]

6.12 Ethique

Harvard Professor's Attack On Pharma's Clinical Trials Is Absurd [Forbes]

A color-coded document Baselga created to explain himself instead illustrated the extent of his confusion and exposure [The Cancer Letter]

6.3 Associations/Fondations

We need to drive up survival rates for the most aggressive cancers [The Telegraph]

6.5 Médecines alternatives/complémentaires

Aromatase inhibitors and acupuncture in breast cancer: Spinning a negative study [Respectful Insolence]

6.6 Publications

How Traditional Publishing Works [The Scholarly Kitchen]

6.7.1 IA/bioinformatique

Google AI Tool Identifies a Tumor's Mutations From an Image [Wired]

6.7.2 Applis

Roche’s NAVIFY decision support portfolio unlocks relevant content from clinical trial and medical publication databases [Roche]

6.9 Controverses

The Cochrane Collaboration—what crisis? [BMJ Blogs]

Mass resignation guts board of prestigious Cochrane Collaboration [Nature]

Let’s stop the burning and the bleeding at Cochrane—there’s too much at stake [BMJ Blogs]