vendredi 3 août 2018

Onco Actu du 3 août 2018

Pour information : Onco Actu suspend sa parution pendant 2 semaines.

1. Biologie

MGH team defines the mechanisms of action of key genetic abnormality in Ewing sarcoma [Massachusetts General Hospital]

Microscopic imaging pierces the “black box” of cancer bone metastasis [MD Anderson Cancer Center]

For prostate cancer, study identifies how common mutation makes good cells go bad [Broad Institute]

2. Etiologie

Update on review of recalled valsartan medicines [EMA]

3.1 Prévention - Tabac

Advancing Tobacco Regulation to Protect Children and Families: Updates and New Initiatives from the FDA on the Anniversary of the Tobacco Control Act and FDA’s Comprehensive Plan for Nicotine [FDA Voice]

4.14 Dép., diag. & prono. - Thyroïde

The Case Against Screening For Thyroid Cancer [FiveThirtyEight]

4.2 Dép., diag. & prono. - Génome

A Road Map for Evaluation and Appropriate Implementation of Genome Sequencing to Improve Population Health [Genomics and Health Impact Blog]

4.5 Dép., diag. & prono. - Colorectal

Regional variations in UK colorectal cancer screening and mortality [The Lancet]

5.1 Traitements - Pré-clinique

New anti-cancer drugs put cancers to sleep…permanently [Walter and Eliza Hall Institute]

5.12.6 Immunothérapies - AMM

New Immunotherapy Option Approved for Cervical Cancer, Rare Lymphoma [NCI]

5.2.1 Pharma - Partenariats

Clovis loses Servier pact, agrees to settle SEC case [FierceBiotech]

5.2.2 Pharma - Fusions & Acquisitions

With high expectations on Provenge, Dendreon is ‘sold’ (again) in $832M deal [EndPoints]

5.2.3 Pharma - économie

Clovis writes a $20 million check payable to the SEC, hoping to rid itself of the lingering roci probe [EndPoints]

BeiGene bags a staggering $903M IPO on the HKEX — and still manages to spark some nervous fretting [EndPoints]

Overpatented, Overpriced: How Excessive Pharmaceutical Patenting is Extending Monopolies and Driving up Drug Prices [I-MAK]

5.3 Traitements - FDA, EMA, NICE...

Brexit forces EMA to suspend tasks as job loss forecast jumps [FierceBiotech]

5.4 Traitements - Economie

Spending On Prescription Drugs In The US: Where Does All The Money Go? [Health Affairs]

6.1 Observation

Breast cancer treatment can double heart risks [The Telegraph]

Testicular Cancer Survivors Have Increased Risk of Developing Subsequent Malignant Neoplasms in the Platinum Era [ESMO]

6.5 Médecines alternatives

FDA blacklists cesium chloride, ineffective and dangerous naturopathic cancer treatment [Science-Based Medicine]

6.7.1 IA/bioinformatique

Smarter cancer treatment: AI tool cuts time of developing radiation therapy plans from days to hours [University of Toronto]