|
1. Biologie
|
|
|
|
2. ÉTIOLOGIE
|
|
|
Bladder Cancer Contrast [Harvard Medical School]
|
|
|
|
|
|
Using
mouse models and human patient data, researchers at Harvard Medical
School and Boston Children’s Hospital found that inherent genomic
differences contribute to the contrast in bladder cancer rate between
the sexes.
|
|
|
|
|
|
|
4. Dépistage, diagnostic et pronostic
|
|
|
|
4.1 Dép., diag. & prono. - Prostate
|
|
|
Men, Beware of Biopsies for Prostate Cancer Dx [MedPage Today]
|
|
|
|
|
|
Initially,
Becker was diagnosed low-risk, low-volume Gleason 6. But his MRI
records were switched. And he was temporarily diagnosed with extensive
prostate cancer. False alarm. He also was hospitalized for potentially
deadly sepsis from an infection caused by a transrectal biopsy. A
nightmare.
|
|
|
|
|
|
|
4.2 Dép., diag. & prono. - Génome
|
|
|
Gene testing of Nigerian women could help prevent breast cancer [UW Medicine]
|
|
|
|
|
|
“It
may seem paradoxical to apply the most recent technology in severely
resource-limited settings,” the authors added, “but in fact the solution
fits the problem… Women with extremely high risk of breast cancer due
to mutations in these genes can be identified inexpensively and
unambiguously, and offered interventions to reduce cancer risk.”
|
|
|
|
|
|
|
4.5 Dép., diag. & prono. - Colorectal
|
|
|
|
5. Traitements
|
|
|
Lasers help fight deadly brain tumors [WUSTL]
|
|
|
|
|
|
A
research team at Washington University School of Medicine in St. Louis
has found that laser treatment designed to destroy the tumor can add an
average of two months to a patient’s life, compared with chemotherapy,
the standard treatment for glioblastomas that have recurred. The
increase is small but meaningful for people who have only months left to
live.
|
|
|
|
|
|
|
5.10 Traitements - Essais
|
|
|
|
5.12 Immunothérapies
|
|
|
|
Immunotherapy Drugs Slow Skin Cancer That Has Spread to the Brain [NY Times]
|
|
|
|
|
|
A
combination of two drugs that activate the immune system shrank brain
tumors in many melanoma patients and prolonged life in a study of 94
people at 28 medical centers in the United States. The drugs were
ipilimumab (brand name Yervoy) and nivolumab (Opdivo), and they belong
to a class called checkpoint inhibitors.
|
|
|
|
|
|
|
5.12.1 Immunothérapies - partenariats
|
|
|
|
|
|
5.12.2 Immunothérapies - CAR-T, thérapies cellulaires
|
|
|
|
5.12.8 Immunothérapies - Economie
|
|
|
|
5.2 Pharma
|
|
|
|
5.3 Traitements - FDA, EMA, NICE...
|
|
|
Real-Time Approval [In the Pipeline]
|
|
|
|
|
|
One
thing to watch is whether the program gets diluted over time, as others
try to move in and get some of the real-time-approval action. It’s fine
if the FDA wants to expand it, but they should only expand it as other
therapeutic areas and trials meet these standards – let them come up to
this level rather than lowering the criteria to meet them.
|
|
|
|
|
|
|
6. Lutte contre les cancers
|
|
|