mardi 21 août 2018

Onco Actu du 21 août 2018

4. Dépistage, diagnostic et pronostic

Helen Macdonald: Overdiagnosis and the fear of being “normal” [BMJ]

4.12 Biopsies liquides

Liquid Biopsy May Predict Risk of Breast Cancer Returning Years Later [NCI]

4.2 Dép., diag. & prono. - Génome

New ESMO tumour DNA scale helps match patients with cancer to optimal targeted medicines [ESMO Press Release]

5.12 Immunothérapies

NCI-led research team develops predictor for immunotherapy response in melanoma [NCI]

5.12.5 Immunothérapies - Pharma

Harbour BioMed jumps into the crowded PD-1/L1 race, looking to take a Chinese asset global as checkpoint pipeline bulges [EndPoints]

5.12.6 Immunothérapies - AMM

FDA Approves Expanded Label for Merck’s KEYTRUDA® (pembrolizumab) in Combination with Pemetrexed (ALIMTA®) and Platinum Chemotherapy for First-Line Treatment of Patients with Metastatic Nonsquamous NSCLC, with No EGFR or ALK Genomic Tumor Aberrations [Merck]

FDA grants regular approval for pembrolizumab in combination with chemotherapy for first-line treatment of metastatic nonsquamous NSCLC [FDA]

FDA grants nivolumab accelerated approval for third-line treatment of metastatic small cell lung cancer [FDA]

5.2.1 Pharma - Partenariats

AbbVie, Tolero team up to test Venclexta combo in AML [FierceBiotech]

5.3.4 Traitements - AMM (FDA, EMA,...)

Tagrisso approved in Japan for 1st-line treatment of EGFR-mutated non-small cell lung cancer [AstraZeneca]

Targeted Drug Approved for Acute Myeloid Leukemia with IDH1 Gene Mutations [NCI]

Ribociclib Approval Expanded for Some Women with Advanced Breast Cancer [NCI]

5.4 Traitements - Economie

NICE stands firm on 'no' vote for Roche's Perjeta in postsurgery breast cancer [FiercePharma]

6.1 Observation

Airline crew don’t have significantly elevated risk of thyroid cancer, new study finds [Stanford Medicine]

Why Are Black And Latino Kids More Likely To Die Of Certain Cancers? [NPR]

6.10.1 Politiques (USA)

Companies report no signs of drugmakers cutting prices, despite Trump pledge [The Hill]

6.4 Médico-éco

A Chinese Pharmacist Found Out He Had Cancer. Then He Vanished. [NY Times]

6.5 Médecines alternatives

Is it likely that alternative medicine works? The importance of prior probability [The Logic of Science]

6.7 DMP, Big Data & applis

Blockchain Startup Shivom Aims High With Precision Medicine Ecosystem [Genome Web]

6.7.1 IA/bioinformatique

Dilemma over AI and drug patenting already under debate [Nature]

6.7.2 Applis

Witty Health Announces Launch of Oncology Provider Registration on OncoPower, a Blockchain-based Digital Health Platform [Witty Health]