jeudi 21 juin 2018

Onco Actu du 21 juin 2018

1. Biologie

Muscle and fat loss may offer clues to pancreatic cancer’s deadly ways [STAT]

2.10 Etiologie - Alcool

Drinking Alcohol Can Raise Cancer Risk. How Much Is Too Much? [NPR]

4.12 Biopsies liquides

Pathology at the forefront of liquid biopsy implementation [PHG Foundation]

4.2 Dép., diag. & prono. - Génome

Barriers to genomic testing get in the way of precision medicine [STAT]

Pancreatic Cancer Risk Linked to Germline Mutations in Six Cancer Predisposition Genes [Genome Web]

4.5 Dép., diag. & prono. - Colorectal

Do Frequent Follow-Up Tests Benefit Colorectal Cancer Survivors? [NCI]

5. Traitements

Drug could protect children from hearing loss after chemo [Cancer Research UK]

Drug 'reduces hearing loss' after childhood cancer treatment [BBC News]

5.1 Traitements - Pré-clinique

Looking Way Down Into the Cells [In the Pipeline]

5.12.3 Immunothérapies-combinaisons

Exploring a New Treatment for Metastatic Colorectal Cancer [Rutgers]

5.12.6 Immunothérapies - AMM

FDA Expands Use of Pembrolizumab to Two Additional Cancer Types [Cancer Research Catalyst]

FDA Alerts Health Care Professionals and Oncology Clinical Investigators about an Efficacy Issue Identified in Clinical Trials for Some Patients Taking Keytruda (pembrolizumab) or Tecentriq (atezolizumab) as Monotherapy to Treat Urothelial Cancer with Low Expression of PD-L1 [FDA]

5.2 Pharma

Biopharma rivals at Roche and Bayer both stand to benefit from the trend toward increased testing of cancer patients [EndPoints]

Finding Cancer Patients Is the Pharma Industry’s Unlikely Challenge [Bloomberg]

5.2.1 Pharma - Partenariats

Novimmune, TG ally to take CD47-CD19 bispecific into clinic [FierceBiotech]

With an AstraZeneca cancer drug in one hand, $37M in the other, Shanghai’s Alpha Bio zooms into a PhII study [EndPoints]

6.1 Observation

Number of elderly diagnosed with cancer set to rocket by 80% in less than 20 years [Cancer Research UK]

Cases of cancer in elderly to surge by 2035, report says [BBC News]

Number of elderly people with cancer 'tipped to soar over next 20 years' [The Telegraph]

Age: the biggest cancer risk factor [Cancer Research UK]

6.10.1 Politiques (USA)

Here come the right-to-try profiteers. The FDA is powerless to stop them [STAT]

6.8 Communication’s 12-year run will end with some nagging questions unanswered [HealthNewsReview]