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2.5 Etiologie - Gènes
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3.1.1 Prévention - Tabac - e-cigs
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4. Dépistage, diagnostic et pronostic
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4.5 Dép., diag. & prono. - Colorectal
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Many journalists fail to question new Cancer Society colorectal cancer screening guidelines [HealthNewsReview]
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As
the New York Times noted last year, a person who was born in 1950 had a
three in a million risk of developing colon cancer in their twenties,
compared with a five per million risk for someone born in 1990. The risk
of rectal cancer for someone in their twenties increased from 0.9 per
million for those born in 1950, compared with 4 per million for someone
born in 1990. Those increases are in the same ballpark as the risk of
being struck by lightning.
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5. Traitements
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5.1 Traitements - Pré-clinique
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5.10 Traitements - Essais
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5.12 Immunothérapies
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IDO Don’ts: After Immunotherapy Failure, Experts Say Slow Down [Xconomy]
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As
buzz about the next promising drug combinations circulates this weekend
at ASCO, the IDO story looms large. Cancer experts say the episode is a
prime example of drug developers moving too fast and, at times, without
scientific rationale or biological insights that might better predict
success.
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5.12.1 Immunothérapies - partenariats
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5.12.2 Immunothérapies - CAR-T
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Tumour tamed by transfer of one T cell [Nature]
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The
T cells of the immune system can be engineered to target a tumour, but
why some people respond better than others to such therapy is unclear.
One patient’s striking response to treatment now offers some clues.
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5.4 Traitements - Economie
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5.5.1.2 ASCO (général) - Académiques
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5.5.10 ASCO (hémato)
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5.5.15 ASCO (biopsies liquides)
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Doctors welcome possible 'holy grail of cancer research' [The Guardian]
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Researchers
said their results showed promise in the approach of blood screenings
for cancer, but noted further “clinical development” was needed. The
number of patients in whom cancers were detected was small. For example,
although the test detected ovarian cancer with 90% accuracy, only 10
ovarian cancers in total were detected.
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5.5.16 ASCO (médecine de précision)
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5.9.3 EHA
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6.10 Politiques
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6.10.1 Politiques (USA)
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FDA Prepares to Implement ‘Right-to-Try’ Law [RAPS]
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“In
the near term,” Woodcock told staff, “if you receive inquiries about
the legislation from patients or physicians about a specific product,
please refer them to the sponsor of the investigational drug or
biological product."
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6.6 Publications
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Collect & Connect - Improved and Updated! [ORCID]
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Based
on our experiences and member feedback, we have worked to clarify the
essential requirements for each badge. Today we are re-launching the
Collect & Connect program, with streamlined guidelines for
implementing ORCID following our best practices.
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6.7 DMP, Big Data & applis
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Big Data and Predictive Analytics - Recalibrating Expectations [JAMA]
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The
potential of prediction to influence decision making also implies the
potential for harm, through the dissemination of misinformation at the
point of care. This potential for harm from insufficiently validated
models in a profit-driven market suggests the need for oversight.
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6.9 Controverses
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Elizabeth Holmes' Superpower [Forbes]
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If
you're reading this to figure out whether to buy the book, just stop
and order it now. Bad Blood is even more nuanced than Carreyrou's
previous reportage, told briskly in muscular prose. I read it fast, I
read it fast again, and then I read it slowly. It is simply one of the
best books about a startup ever.
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