jeudi 14 juin 2018

Onco Actu du 14 juin 2018

1.4 Biologie - Technos

Could Cancer Risk Claw CRISPR’s Potential? Some Balanced Perspectives [The Niche]

3.1 Prévention - Tabac

Tobacco industry seeking to control anti-smuggling measures, say critics [The Guardian]

3.3 Prévention - Vaccins

Merck's Keytruda snags I-O's first cervical cancer nod to back up HPV fighter Gardasil [FiercePharma]

FDA Grants Priority Review to Merck’s Supplemental Biologics License Application (sBLA) for GARDASIL®9 in Women and Men Ages 27 to 45 for the Prevention of Certain HPV-Related Cancers and Diseases [Merck]

A dumpster fire of a study about HPV vaccination and female fertility, courtesy of Gayle Delong [Respectful Insolence]

5. Traitements

The Search for Cancer Treatment That Is Personal and Useful [NY Times]

5.1 Traitements - Pré-clinique

Blocking energy production could help treat lung cancer where chemotherapy has limited effect [Insstitute of Cancer Research]

5.10 Traitements - Essais

Unreported clinical trial of the week: A prostate cancer vaccine in combination with flutamide (NCT00450463) [BMJ]

5.12 Immunothérapies

Older Melanoma Patients May Respond to Anti-PD1 Immunotherapy Better Than Younger Patients [AACR]

5.2 Pharma

Seattle Genetics Announces First Patient Dosed in Phase 2 Trial of Tisotumab Vedotin for Women with Recurrent or Metastatic Cervical Cancer [Seattle Genetics]

5.3.4 Traitements - AMM (FDA, EMA,...)

FDA Approves Merck’s KEYTRUDA® (pembrolizumab) for Treatment of Refractory or Relapsed Primary Mediastinal Large B-Cell Lymphoma (PMBCL) [Merck]

FDA approves Roche’s Avastin (bevacizumab) plus chemotherapy as a treatment for women with advanced ovarian cancer following initial surgery [Roche]

FDA approves pembrolizumab for treatment of relapsed or refractory PMBCL [FDA]

FDA approves bevacizumab in combination with chemotherapy for ovarian cancer [FDA]

5.9 AACR

Q&A With Ari M. Melnick, MD, on Recent Advances in Lymphoma [Cancer Research Catalyst]

6. Lutte contre les cancers

I handed over my genetic data to the NIH. Here’s why you should, too [STAT]

6.1 Observation

Huge study shows cancer benefits, limitations of antiretroviral therapy for HIV [Stanford Medicine]

Race may be factor in who completes breast cancer chemotherapy [Reuters]