jeudi 31 mai 2018

Onco Actu du 31 mai 2018

1. Biologie

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine Proceedings of a Workshop (2018) [National Academies Press]

Mathematical model explains why metastasis can occur even when cancer is caught early [Penn Today]

3. Prévention

Everyday changes to diet and exercise could avoid 26,000 cases of cancer a year in women [Cancer Research UK]

3.1 Prévention - Tabac

Smoking down, but tobacco use still a major cause of death, disease - WHO [Reuters]

4.5 Dép., diag. & prono. - Colorectal

American Cancer Society Updates Colorectal Cancer Screening Guideline [ACS]

Get Screened Earlier For Colorectal Cancer, Urges American Cancer Society [NPR]

Cancer group says colon screening should start at 45, not 50 [STAT]

Colon and rectal cancer screenings should start at 45, new guidelines say [CNN]

Cancer Group Calls for Colorectal Cancer Screening Starting at Age 45 [NY Times]

5.12.1 Immunothérapies - partenariats

Following ASCO preview flop, Syndax bets on new combo deal with Nektar [EndPoints]

5.12.2 Immunothérapies - CAR-T

Janssen Announces Initiation of Phase 1b/2 Clinical Development Program Evaluating JNJ-68284528 CAR-T Cells for the Treatment of Multiple Myeloma [Janssen]

J&J hustles Legend’s promising BCMA CAR-T into PhI/II trial, winning an FDA green light to begin recruiting patients [EndPoints]

5.12.5 Immunothérapies - Pharma

Eying Clinical Trials, Shattuck Labs Adds $46M for Immunotherapy R&D [FierceBiotech]

5.12.7 Immunothérapies - vaccins

Brain cancer vaccine effective in some patients [WUSTL]

Northwest Bio's long-awaited glioblastoma vaccine data see stock roller coaster [FierceBiotech]

A Glioblastoma Vaccine? Not Yet. [In the Pipeline]

5.2 Pharma

New report and resources put cancer in context, showing more than 1,100 medicines and vaccines in development [PhRMA]

Clovis Oncology Announces European Commission Authorization Of Rubraca® (Rucaparib) For Women With Recurrent Ovarian Cancer [Clovis Oncology]

5.3 Traitements - FDA, EMA, NICE...

Calling Out the FDA's 'We Don't Regulate Medicine' Mantra [Vinay Prasad-Medscape]

6.10.1 Politiques (USA)

Trump signs right-to-try legislation, making controversial measure law of the land [STAT]

Trump signs ‘right-to-try’ bill, says voluntary drug price cuts coming in two weeks [EndPoints]

Trump says drug companies to announce 'massive' price cuts soon [Reuters]

6.6 Publications

Who gets credit? Survey digs into the thorny question of authorship [Nature]

6.7.1 IA/bioinformatique

For Some Hard-To-Find Tumors, Doctors See Promise In Artificial Intelligence [NPR]

6.9 Controverses

DNA donors must demand stronger protection for genetic privacy [STAT]