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1. Biologie
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2. Etiologie
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4.2 Dép., diag. & prono. - Génome
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5. Traitements
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5.1 Traitements - Pré-clinique
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Experimental Cancer Drug Metarrestin Targets Metastatic Tumors [NCI]
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In
mice with pancreatic cancer that had spread to other organs, treatment
with the drug—called metarrestin—shrank metastatic tumors and greatly
extended how long the mice lived. The drug appeared to be generally
safe, with no evidence that it harmed the organs where metastatic tumors
had formed or the mice in any way that the researchers could measure.
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Unexpected efficacy against aggressive cancers [TUM]
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Using
a mouse model and samples taken from cancer patients, a team from the
Technical University of Munich (TUM) has shown that a new class of drugs
known as SHP2 inhibitors is also effective against aggressive,
hard-to-treat tumors such as lung and pancreatic cancers. Clinical
trials currently underway had previously excluded patients with these
cancers.
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5.10 Traitements - Essais
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5.12.2 Immunothérapies - CAR-T
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5.12.3 Immunothérapies-combinaisons
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5.12.5 Immunothérapies - Pharma
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5.12.7 Immunothérapies - vaccins
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Brain cancer vaccine could extend lives of patients by years [The Guardian]
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“Although
definitive judgment needs to be reserved until the final data is
available, the paper published today hints at a major breakthrough in
the treatment of patients with glioblastoma,” he said. “Cautious
optimism is welcome in an area where for so long the disease and
suffering have had the upper hand.”
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5.2 Pharma
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5.2.1 Pharma - Partenariats
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5.3 Traitements - FDA, EMA, NICE...
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5.4 Traitements - Economie
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5.5.11 ASCO (SNC]
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6.1 Observation
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Report: Ovarian Cancer Rates Continue to Decrease [ACS]
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In
contrast to overall trends, which are driven by older ages, incidence
of ovarian cancer among women under 65 has generally declined since at
least 1975, probably reflecting uptake of oral contraceptives, which are
known to reduce risk of ovarian cancer.
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6.10.1 Politiques (USA)
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6.7 DMP, Big Data & applis
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6.7.1 IA/bioinformatique
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6.8 Communication
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6 tips to spot cancer ‘fake news’ [Cancer Research UK]
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None
of this is trying to talk down research or the news stories it
generates. Science should be as accessible as possible, and we’re lucky
that cancer news attracts as much interest as it does. But this leaves
room for distortion.
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