jeudi 3 mai 2018

Onco Actu du 3 mai 2018

1. Biologie

Understanding the mutations that drive myeloma, a cancer of the bone marrow [Institute of Cancer Research]

2.4 Etiologie - Portables, ondes e-m

Mobile phone cancer warning as malignant brain tumours double [The Telegraph]

2.6 Etiologie - Environnement

Studies Examine Possible Cancer Risks for Firefighters at World Trade Center [ACS]

3.1.1 Prévention - Tabac - e-cigs

Potential Public Health Effects of Reducing Nicotine Levels in Cigarettes in the United States [NEJM]

Federal Government Sends Warning To Vaping Companies [NPR]

4. Dépistage, diagnostic et pronostic

Pill for breast cancer diagnosis may outperform mammograms [University of Michigan]

4.11 Dép., diag. & prono. - Ovaire

Study Shows Experimental Screening Test Can Detect Endometrial and Ovarian Cancers [NCI]

4.2 Dép., diag. & prono. - Génome

Increased Germline and Tumour Mutation Testing Recommended in Adolescent and Young Adults with Cancer [ESMO]

Cancer Sequencing Hype And Reality [In the Pipeline]

4.9 Dép., diag. & prono. - Sein

450,000 women missed out on breast screening appointments 'due to computer error' [Cancer Research UK]

Jeremy Hunt launches inquiry into 450,000 missed breast cancer screenings [The Guardian]

The computer glitch that led to the breast screening disaster [The Guardian]

Breast scan error 'shortened up to 270 lives' - Hunt [BBC News]

Serious failure in English breast cancer screening may have shortened lives: minister [Reuters]

5.12.10 Immunothérapies - Fusions et acquisitions

Janssen to Acquire BeneVir Biopharm to Advance Immunotherapy Regimens [Janssen]

Playing the long game in I/O, J&J inks $1.04B deal to buy oncolytic virus platform biotech BeneVir [EndPoints]

5.12.2 Immunothérapies - CAR-T

CAR-T Immunotherapy Eliminates Metastatic Colorectal Cancer in Mice [Thomas Jefferson University]

Cellectis Files IND for UCART22 in Acute Lymphoblastic Leukemia (B-ALL) [Cellectis]

5.2.1 Pharma - Partenariats

Exelixis and Invenra Enter Into Collaboration to Discover and Develop Novel Biologics to Treat Cancer [Exelixis]

Bristol-Myers Squibb and Flatiron Health Expand Collaboration with a Three-Year Agreement [BMS]

Flatiron Health, Purchased By Roche, Signs Three-Year Deal With Bristol-Myers [Forbes]

5.2.3 Pharma - économie

Sandoz receives complete response letter from the US FDA for proposed biosimilar rituximab [Novartis]

Pharma’s broken business model — Part 2: Scraping the barrel in drug discovery [EndPoints]

Roche wins reprieve as Novartis biosimilar delayed in U.S. [Reuters]

Too many cancer drugs? Crowded market gives investors pause [Reuters]

5.9 AACR

Highlights from the AACR Annual Meeting 2018 [Cancer Research Catalyst]

6.1 Observation

'DES daughters' with rare cancer continue to face higher death rates [Reuters]

6.10 Politiques

European Commission proposes €100 billion research spending plan [Science]

6.6 Publications

Accused cancer scientist resigns as editor of prestigious journal [Science]

Dr Magdalena Skipper appointed new Editor-in-Chief of Nature [Nature]

6.7.1 IA/bioinformatique

Daphne Koller, A-list backers unite to create machine learning drug R&D startup [FierceBiotech]