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1.4 Biologie - Technos
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Genomenon and Saphetor Announce Collaboration to Share Genomic Data [Xconomy]
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Last
year, Genomenon went live with Mastermind, a search engine that combs
through millions of publicly available medical journal articles to
connect a patient’s genomic data with the latest scientific literature,
simplifying the diagnostic process. Saphetor maintains VarSome, a gene
and variant database with 47,000 users worldwide and more than 33
billion data points.
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2.11 Etiologie - Alimentation
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3.1 Prévention - Tabac
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Big tobacco’s offer: $1 billion for research. Should scientists take it? [Science]
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The
big question is how many researchers will want a share of PMI's $1
billion. "I would be very surprised if reputable researchers applied,"
says Martin McKee of the London School of Hygiene & Tropical
Medicine. But Yach says he's already received 50 to 60 proposals from
around the world, including from U.S. medical schools.
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3.8 Prévention - Alimentation
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No, Asparagus Won't Give You Cancer [ACSH]
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Why
was this rather boring molecule that biology majors are forced to
memorize grabbing international headlines? Because, according to the
media, it causes cancer. And where can you find asparagine? It can be
found in any food that contains protein -- which is a lot of foods --
including asparagus, the vegetable after which it was named. Thus,
asparagus causes cancer. Think I'm joking? I'm not.
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4.10 Dép., diag. & prono. - FDA, EMA, NICE,...
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4.2 Dép., diag. & prono. - Génome
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4.9 Dép., diag. & prono. - Sein
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5.10 Traitements - Essais
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Many mutations in one clinical-trial basket [Nature]
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When
abnormality in a gene is linked to cancer and a drug targets the
encoded protein, how can the patients who will respond to the drug be
identified if the gene is mutated in many different ways in many
different cancers?
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5.12 Immunothérapies
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5.12.2 Immunothérapies - CAR-T
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5.3.4 Traitements - AMM (FDA, EMA,...)
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FDA Approves New Treatment for Certain Neuroendocrine Tumors [NCI]
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On
January 29, the Food and Drug Administration (FDA) approved a new
targeted treatment, lutetium Lu 177 dotatate (Lutathera®), for adult
patients with advanced NETs that affect the pancreas or gastrointestinal
tract, known as GEP-NETs. Lutetium Lu 177 dotatate is the first
radioactive drug approved to treat these rare cancers.
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5.5 ASCO
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5.5.3 ASCO (prostate)
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Two Prostate Cancer Drugs Delay Spread of the Disease by Two Years [NY Times]
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The
study of an experimental drug called apalutamide was published Thursday
in the New England Journal of Medicine. The other study of a drug
called enzalutamide, currently approved for treating prostate cancer
that has already metastasized, has not yet been peer-reviewed for
publication, the authors said.
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5.6 ESMO
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Teleconsulting to Bring Specialised Expertise in Rare Cancers Across Europe [ESMO]
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In
this framework, the core business of EURACAN reference centres will be
teleconsulting: the idea behind this information technology platform,
currently under development, is that the expertise of the reference
centres will be made available to all healthcare providers wherever they
are, saving patients from having to travel for treatment.
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6. Lutte contre les cancers
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6.10 Politiques
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6.4 Médico-éco
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Waiting to Treat the Cancer [NY Times]
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All
in, the transplant and its necessary follow-up would cost around half a
million dollars. Time was of the essence – he could receive the
transplant only if he remained in a remission. Another week passed. And
another week. The wait was maddening. We phoned his insurance company
again, but they put us off, saying that his “case” was being reviewed.
It wouldn’t be long before the leukemia cropped up again.
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