vendredi 2 février 2018

Onco Actu du 2 février 2018

1. Biologie

Bacteria Play Critical Role In Driving Colon Cancers [Johns Hopkins]

1.1 Biologie - Gènes

Fusions in Solid Tumours [ESMO]

4.7 Dép., diag. & prono. - Col de l'utérus

Thousands of cancer tests to be checked after women wrongly given the all clear [The Telegraph]

5. Traitements

Fine-tuning cancer medicine [MIT News]

5.12.1 Immunothérapies - partenariats

AstraZeneca, Syndax ally to test PD-L1 drug and CSF1R inhibitor in solid tumor patients [FierceBiotech]

5.12.5 Immunothérapies - Pharma

Biotech’s biggest unicorn is now worth $7.5 billion [STAT]

Despite Doubters, Moderna Raises $500 Million, Is Now Worth $7 Billion [Forbes]

5.12.7 Immunothérapies - vaccins

Cancer ‘vaccine’ eliminates tumors in mice [Stanford Medicine]

Locally-Injected Immunotherapy Eradicates Tumors in Mice [The Scientist]

5.2 Pharma

After EMA flop, Puma takes Nerlynx to China in new out-licensing deal [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

Tianjing Li: What’s not shared—building on the FDA’s transparency momentum [BMJ]

5.3.4 Traitements - AMM (FDA, EMA,...)

Record number of personalized medicines approved in 2017 [PhRMA]

5.4 Traitements - Economie

What’s at stake if U.S. drug prices fall? [Healthcare Economist]

As states target high drug prices, pharma targets state lawmakers [STAT]

6. Lutte contre les cancers

World Cancer Day: Get the Facts [AACR]

6.1 Observation

Why should the poor die young? Closing the gap in cancer outcomes [The Guardian]

Prostate cancer deaths overtake those from breast cancer [BBC News]

Prostate cancer now kills more people than breast cancer, UK figures reveal [The Guardian]

6.10.1 Politiques (USA)

I’m the ideal person to support right to try. But I can’t — it’s a disaster in the making [STAT]

Trump's 'Right To Try' Push Would Only Punish The Seriously Ill [Forbes]

LCA Praises Bipartisan, Bicameral Congressional Leadership on Women’s Health Imperative [Lung Cancer Alliance]

6.7 DMP, Big Data & applis

An incredibly important paper on whether data can ever be "anonymized" and how we should handle release of large data-sets [Boing Boing]

6.9 Controverses

Richard Smith: Doctors and patients heading in opposite directions [BMJ Blogs]