jeudi 1 février 2018

Onco Actu du 1er février 2018

1. Biologie

Technology to watch in 2018 [Nature]

2.7 Etiologie - Obésité

Disrupting a Link Between Obesity and Cancer [Cancer Research Catalyst]

3.1 Prévention - Tabac

CDC director’s investment in tobacco, drug companies baffles ethics experts [STAT]

Who’s Still Smoking: Report Highlights Populations Still at Risk [ACS]

CDC director resigns after report on tobacco stock purchase [Science]

Exclusive: With Roman law doctrine, India moves to stub out tobacco industry rights [Reuters]

3.1.1 Prévention - Tabac - e-cigs

Two U.S. lawmakers voice concerns over Philip Morris tobacco trials [Reuters]

3.6 Prévention - Activité physique

Even obese breast cancer survivors may cut heart disease risk with exercise [Reuters]

5.1 Traitements - Pré-clinique

Blocking cancer stress signal shows promise in bone marrow cancer [Institute of Cancer Research]

5.12.2 Immunothérapies - CAR-T

Novartis announces NEJM publication of updated analysis from ELIANA trial showing longer-term durable remissions with Kymriah(TM) in children, young adults with r/r ALL [Novartis]

5.2 Pharma

Roche silently scraps two one-time blockbuster hopefuls as $725M Seragon deal craters [EndPoints]

Analysis: Pfizer tallies an impressive array of late-stage catalysts for cancer, gene therapies and more [EndPoints]

5.2.2 Pharma - Fusions & Acquisitions

Seattle Genetics to Acquire Cascadian Therapeutics, Adding Late-Stage Breast Cancer Program to Its Oncology Pipeline [Seattle Genetics]

Seattle Genetics sets $614M buyout of Cascadian and its breast cancer program [FierceBiotech]

Restless Seattle Genetics snaps up a pivotal-stage cancer drug with $614M Cascadian buyout pact [EndPoints]

5.2.3 Pharma - économie

Startup with Johns Hopkins roots raising $40.5 million to develop cancer metabolism drugs [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

How to better apply the paediatric legislation to boost development of medicines for children [EMA]

EU decision on EMA move to Amsterdam is done: EU Commissioner [Reuters]

5.4 Traitements - Economie

NICE approves Perjeta for routine use on NHS [Pharmafile]

Q&A: Commission proposal on Health Technology Assessment [European Commission]

EU proposes joint studies to speed acceptance of new medicine [Reuters]

Nice approves life-extending drug for patients with incurable breast cancer [The Guardian]

6. Lutte contre les cancers

NHS radiotherapy changes could see more patients having modern treatment [Cancer Research UK]

6.1 Observation

Cancer survival improving globally, but UK lagging behind [Cancer Research UK]

6.11 Patients

After a Cancer Diagnosis, Playing the Odds [NY Times]

6.13 Soins palliatifs

I’m a doctor with end-stage cancer. I support medical aid in dying [STAT]

6.6 Publications

The serendipity test [Nature]

6.7 DMP, Big Data & applis

Elekta Taps IBM Watson Health to Bring AI to Comprehensive Oncology Field [Elekta]

6.8 Communication

Heart group warns of cardiovascular risks after treatment for breast cancer [STAT]

Breast cancer treatments can raise risk of heart disease, American Heart Association warns [Washington Post]

6.9 Controverses

Take peer pressure out of peer review [Nature]