vendredi 16 février 2018

Onco Actu du 16 février 2018

2.11 Etiologie - Alimentation

Highly Processed Foods & Cancer Risk [ACS]

‘Ultra-processed’ foods and cancer: Headlines show the right way, and the wrong way, to frame study results [HealthNewsReview]

2.5 Etiologie - Gènes

Fathers may pass ovarian cancer risk to daughters [BBC News]

4.9 Dép., diag. & prono. - Sein

JAMA Oncology Publication Demonstrates EndoPredict® (EPClin) Significantly Outperforms Oncotype DX® Recurrence Score in Early-Stage Breast Cancer [Myriad]

Breast cancer relapse tests vary in accuracy [Cancer Research UK]

Breast MRIs may lead to more biopsies that catch fewer cancers [Reuters]

5.12 Immunothérapies

Analysis of the clinical immuno-oncology landscape [Nature]

Leading Cancer Organizations Provide Guidance on Understanding and Managing Immunotherapy Side Effects [ASCO]

5.12.2 Immunothérapies - CAR-T

Celgene spinoff debuts with big names, big bucks and big hopes [FierceBiotech]

Celularity Raises $250M to Make Stem Cell Treatments for Cancer & More [Xconomy]

Celgene Spinout Celularity Raises $250 Million To Develop Placental Cells To Attack Cancer [Forbes]

5.12.4 Immunothérapies - Essais

Pfizer, Merck KGaA say their PD-L1 Bavencio also flunked PhIII in the all-important lung cancer field [EndPoints]

Merck KGaA, Pfizer's immunotherapy fails in lung cancer trial [Reuters]

Merck and Pfizer Provide Update on Phase III JAVELIN Lung 200 Trial of Avelumab Monotherapy in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer [Merck]

5.2 Pharma

French pharma group Ipsen sees more asset purchases, U.S. growth [Reuters]

5.2.2 Pharma - Fusions & Acquisitions

Roche To Buy Big Data Upstart Flatiron Health For $1.9 Billion [Forbes]

Roche to Acquire Cancer Software Startup Flatiron Health for $1.9B [Xconomy]

Roche pays $1.9B for Ex-Googlers’ tech startup Flatiron Health [EndPoints]

Roche to buy Flatiron Health for $1.9 billion to expand cancer care portfolio [Reuters]

Roche to acquire Flatiron Health to accelerate industry-wide development and delivery of breakthrough medicines for patients with cancer [Roche]

Alphabet-backed Flatiron Health is being acquired by Roche [CNBC]

5.3.4 Traitements - AMM (FDA, EMA,...)

Abiraterone Approved for Earlier Use in Men with Metastatic Prostate Cancer [NCI]

5.4 Traitements - Economie

Drugs approved in Scotland for bladder and skin cancers [Cancer Research UK]

Alternative treatments for people with thyroid cancer to be offered routinely on the NHS, says NICE [NICE]

6.7.1 Bioinformatique

Machine Learning for Building Personalized Cancer Nanomedicines: Interview with Dr. Daniel Heller [MedGadget]

6.7.2 Applis

Wanted: a WhatsApp alternative for clinicians [BMJ]