jeudi 15 février 2018

Onco Actu du 15 février 2018

1. Biologie

Researchers define structure, function of enzyme key to blood cancers [UNC]

Science self-corrects: cancer gene does not pass reproducibility test [Cold Spring Harbor Lab]

2.11 Etiologie - Alimentation

Cancer warning over processed foods that make up half of UK diet [The Telegraph]

Ultra-processed foods may be linked to cancer, says study [The Guardian]

5.1 Traitements - Pré-clinique

Cutting off cervical cancer’s fuel supply stymies tumors [WUSTL]

5.10 Traitements - Essais

DNAnexus’ new solution integrates next-generation sequencing data in clinical trials [FierceBiotech]

Cancer Research UK to invest £45 million in clinical trials [Cancer Research UK]

5.12 Immunothérapies

For Rare Melanoma, Checkpoint Inhibitors May Hold Substantial Promise [NCI]

5.12.1 Immunothérapies - partenariats

Bristol-Myers Squibb and Nektar Therapeutics Announce Global Development & Commercialization Collaboration for Nektar’s CD122-biased Agonist, NKTR-214 [BMS]

Bristol-Myers Bets Nearly $2B on Nektar for an Immunotherapy Boost [Xconomy]

Bristol-Myers Squibb makes history with major multibillion-dollar Nektar drug pact [FierceBiotech]

Pay Your Money and Hold Your Breath [In the Pipeline]

Bristol, needing a cancer immunotherapy boost, pays shockingly steep price for Nektar drug [STAT]

Bristol-Myers lassos the next big thing in I/O, grabs ‘214 rights in a record $3.6B deal with Nektar [EndPoints]

Nektar Gets a Payday But No Mega-Buyout [Bloomberg]

Bristol-Myers To Pay Largest Fee In Biotech History For Nektar Cancer Drug [Forbes]

Bristol-Myers to pay $1.85 billion in cancer deal with Nektar [Reuters]

5.12.5 Immunothérapies - Pharma

Merck says Keytruda's explosive growth prompts need for new Ireland plant with 350 jobs [FiercePharma]

5.12.7 Immunothérapies - vaccins

Cancer-Killing Virus Acts by Alerting Immune System [UCSF]

5.3.4 Traitements - AMM (FDA, EMA,...)

ERLEADA (apalutamide), a Next-Generation Androgen Receptor Inhibitor, Granted U.S. FDA Approval for the Treatment of Patients with Non-Metastatic Castration-Resistant Prostate Cancer [Janssen]

J&J wins snap approval of apalutamide, the first drug OK’d for nonmetastatic prostate cancer [EndPoints]

FDA approves J&J prostate cancer treatment [Reuters]

FDA approves apalutamide for non-metastatic castration-resistant prostate cancer [FDA]

FDA approves new treatment for a certain type of prostate cancer using novel clinical trial endpoint [FDA]

5.4 Traitements - Economie

Do expensive drugs reduce the price of health? [Healthcare Economist]

6.10.1 Politiques (USA)

Trump presses key Republican to move on ‘right to try’ [STAT]

6.7.2 Applis

Medical Records May Finally Be Coming To Your Apple Smartphone [NPR]

6.7.3 DMP

Digital divide persists with online portals for cancer patients [Reuters]