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1. Biologie
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3.1.1 Prévention - Tabac - e-cigs
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3.6 Prévention - Activité physique
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4.2 Dép., diag. & prono. - Génome
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5. Traitements
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The Drug Development Paradigm in Oncology Proceedings of a Workshop (2018) [National Academies Press]
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This
workshop convened cancer researchers, patient advocates, and
representatives from industry, academia, and government to discuss
challenges with traditional approaches to drug development,
opportunities to improve the efficiency of drug development, and
strategies to enhance the information available about a cancer therapy
throughout its life cycle in order to improve its use in clinical
practice.
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5.1 Traitements - Pré-clinique
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DNA Robots Target Cancer [The Scientist]
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The
authors showed in the study that the nanorobots didn’t cause clotting
in major tissues in miniature pigs, which satisfies some safety
concerns, but Yan agrees that more work is needed. “We are interested in
looking further into the practicalities of this work in mouse models,”
he writes.
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5.10 Traitements - Essais
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5.12 Immunothérapies
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5.12.5 Immunothérapies - Pharma
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5.2 Pharma
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5.2.3 Pharma - économie
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5.3.4 Traitements - AMM (FDA, EMA,...)
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5.4 Traitements - Economie
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NICE backs EUSA’s kidney cancer drug Fotivda [PharmaTimes]
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In
clinical trials, patients treated with Fotivda (tivozanib) experienced
superior progression free survival - 11.9 versus 9.1 months in the
overall population and 12.7 versus 9.1 months in treatment naïve
patients - versus Bayer’s Nexavar (sorafenib).
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Contribution of NIH funding to new drug approvals 2010–2016 [PNAS]
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This
analysis, which captures basic research on biological targets as well
as applied research on NMEs, suggests that the NIH contribution to
research associated with new drug approvals is greater than previously
appreciated and highlights the risk of reducing federal funding for
basic biomedical research.
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5.5 ASCO
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6.1 Observation
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6.10.1 Politiques (USA)
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6.6 Publications
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6.9 Controverses
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