lundi 22 janvier 2018

Onco Actu du 22 janvier 2018

1. Biologie

Two New Breast Cancer Genes Emerge from Study of Lynch Syndrome [Columbia University]

How Cancer Metastasis Happens: Researchers Reveal a Key Mechanism [Weill Cornell]

Can Molecular Analysis be Tapped to Tackle Brain Cancer? [Cancer research Catalyst]

3.1 Prévention - Tabac

Anti-smoking plan may kill cigarettes — and save Big Tobacco [STAT]

FDA's tobacco stance faces test with Philip Morris iQOS device [Reuters]

4.10 Dép., diag. & prono. - FDA, EMA, NICE,...

NICE Issues Medtech Innovation Briefing on Plasma EGFR Mutation Tests for Adults with Locally Advanced or Metastatic NSCLC [ESMO]

4.12 Biopsies liquides

A routine blood test for cancer would be fantastic. Today’s news isn’t it [Cancer Research UK]

Detecting cancer with a blood test: New study shows promise, but questions remain [ACS]

4.7 Dép., diag. & prono. - Col de l'utérus

Embarrassment makes women avoid smear tests, charity says [BBC News]

Whatever happened to the Jade Goody effect? [The Guardian]

5. Traitements

Nilotinib Can Be Discontinued in Some Patients with Chronic Myelogenous Leukemia [NCI]

Music, Science, PARP And The Meaning Of A New Drug For Metastatic Breast Cancer With BRCA Mutations [Forbes]

5.1 Traitements - Pré-clinique

New treatment strategy could overcome drug resistance in testicular cancer [Institute of Cancer Research]

5.12.2 Immunothérapies - CAR-T

CRISPR Trial for Cancer Patients Proposed [The Scientist]

China, Unhampered by Rules, Races Ahead in Gene-Editing Trials [Wall Street Journal]

5.2 Pharma

U.S. FDA Grants Priority Review for Daratumumab in Front Line Multiple Myeloma [Genmab]

5.2.2 Pharma - Fusions & Acquisitions

Sanofi to buy U.S. haemophilia group Bioverativ for $11.6 billion [Reuters]

5.2.3 Pharma - économie

PharmaMar stock tanks after PhIII ovarian cancer study flops [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

The One-Year Anniversary of the Oncology Center of Excellence [FDA Voice]

5.3.4 Traitements - AMM (FDA, EMA,...)

AstraZeneca scores double approvals in Japan for asthma and ovarian cancer [Pharmafile]

5.4 Traitements - Economie

Hospitals Making Drugs? [In the Pipeline]

5.5 ASCO

Exelixis Announces Presentation of Updated Phase 1b Results for the Combination of Cobimetinib and Atezolizumab in Metastatic Colorectal Cancer at the 2018 American Society of Clinical Oncology Gastrointestinal Cancers Symposium [Exelixis]

AVEO Oncology Announces Presentation of Data from Phase 1b/2 Study of Tivozanib in Patients with Advanced Hepatocellular Carcinoma [Aveo]

Opdivo (nivolumab) in Combination with Yervoy (ipilimumab) Demonstrates Clinical Activity in Previously Treated Patients with dMMR or MSI-H Metastatic Colorectal Cancer [BMS]

Combination of Encorafenib, Binimetinib and Cetuximab Demonstrated an 8 Month Median Progression-Free Survival in BRAF-Mutant Colorectal Cancer in Updated Safety Lead-In Results from BEACON Phase 3 Trial [Array]

6. Lutte contre les cancers

Cancer Patients Get Little Guidance From Doctors On Using Medical Marijuana [NPR]

6.1 Observation

Proportion of cancers diagnosed in A&E falling [Cancer Research UK]

Oral Contraceptives Reduce Risk for Ovarian and Endometrial Cancers [NY Times]

6.10.1 Politiques (USA)

The Koch Brothers and Vice President Mike Pence back a final push to pass the cruel sham known as “right-to-try” [Respectful Insolence]

Science groups react to U.S. government shutdown as researchers scramble [Science]

6.13 Soins palliatifs

I watched my son die from cancer. Here are the lessons I have learned [The Guardian]