jeudi 18 janvier 2018

Onco Actu du 18 janvier 2018

1. Biologie

How cancer outsmarts multicellularity [The Darwin Cancer Blog]

Chemistry 'Van Gogh' could help with cancer [BBC News]

3.3 Prévention - Vaccins

Did Gardasil kill Colton Berrett? The answer is almost certainly no. [Respectful Insolence]

4. Dépistage, diagnostic et pronostic

HalioDx Closed A Series B Round of €18.5 Million [HalioDx]

4.12 Biopsies liquides

Startups Race to Create Cancer Screens from DNA [Wired]

4.9 Dép., diag. & prono. - Sein

Angelina Jolie gene testing for all? [BBC News]

5. Traitements

Pipeline Looks Strong for 2018 New Oncology Drugs [Clinical Oncology News]

5.1 Traitements - Pré-clinique

New way to target the growth of breast cancer cells [Karolinska Institutet]

5.10 Traitements - Essais

It’s time to levy penalties for failing to report clinical trial results [STAT]

Heated abdominal chemo bath improves ovarian cancer survival [Reuters]

5.12.10 Immunothérapies - Fusions et acquisitions

Celgene Needs a Boost, But Juno Isn't It [Bloomberg]

5.12.2 Immunothérapies - CAR-T

Seeking to expand CAR-T's reach, Novartis snags new regulatory milestones for Kymriah [FiercePharma]

U.S. Doctors Plan to Treat Cancer Patients Using CRISPR [MIT Technology Review]

5.12.5 Immunothérapies - Pharma

First Patient Dosed in a Phase 2 Trial with Transgene’s TG4010 + Nivolumab + Chemotherapy for the First-Line Treatment of Lung Cancer (NSCLC) [Transgene]

5.2 Pharma

Boehringer's Gilotrif widens its reach in crowded EGFR lung cancer field [FiercePharma]

5.2.3 Pharma - économie

With Pfizer in hot pursuit, J&J loses a critical patent fight as it scrambles for a new prostate cancer drug OK [EndPoints]

U.S. court invalidates patent on J&J cancer drug Zytiga [Reuters]

5.3 Traitements - FDA, EMA, NICE...

FDA chief Gottlieb backs away from plan to publish CRLs [FierceBiotech]

Is an orphan medicine still an orphan once it gets on the market? [EMA]

EMA Begins Publishing Reports on Whether Approved Medicines Still Qualify as Orphans [RAPS]

An open letter to Dr. Scott Gottlieb on FDA transparency [STAT]

5.4 Traitements - Economie

Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer [NICE]

NICE shoots down Pfizer's Xalkori in ROS1-positive patients, inviting a CDF proposal instead [FiercePharma]

NICE approves CDF funding for Janssen’s Darzalex [PharmaTimes]

Pfizer asked to submit CDF proposal for Xalkori [PharmaTimes]

Fed Up With Drug Companies, Hospitals Decide to Start Their Own [NY Times]

5.5 ASCO

Bayer to highlight new research at ASCO GI 2018 Cancer Symposium [Bayer]

6.1 Observation

More evidence of link between severe gum disease and cancer risk [Tufts]

6.10 Politiques

Doctors should order more blood cancer tests, MPs say [The Guardian]

The All Party Parliamentary Group on Blood Cancer (APPGBC) raises awareness and promotes the needs of blood cancer patients with parliamentarians, government, NHS, and charity stakeholders - and much more [Bloodwise]

6.7 DMP, Big Data & applis

CancerLinQ LLC Enters Collaboration With the Association for Molecular Pathology [ASCO]

6.7.1 Bioinformatique

OWKIN Closes $11 Million Series A Financing Round [Business Wire]

6.9 Controverses

EPO Revokes Broad’s CRISPR Patent [The Scientist]

Most medical practices are not parachutes: a citation analysis of practices felt by biomedical authors to be analogous to parachutes [CMAJ Open]