Onco Actu du 12 janvier 2018

	3.1.1 Prévention - Tabac - e-cigs
Public Health Consequences of E-Cigarettes: Report Release Webinar [National Academies] Six members from the Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems (ENDS) of the National Academies of Sciences, Engineering, and Medicine will present the findings of the committee, which will be available online at 11 AM on January 23, 2018.
	5. Traitements
Some leukaemia patients may be missing out on new treatments [Queen Mary university of London] By analysing cell samples from 36 patients with acute myeloid leukaemia (AML), the research team unexpectedly found that mutations on FLT3 were not a good predictor of whether or not the drug would be beneficial to a patient. Instead, they found that protein markers were able to identify which patients would respond to the drug with much greater accuracy.
Medical Marijuana: Where is the evidence? [Science-Based Medicine] If marijuana is to be treated as medicine, then it needs to meet the same standards of quality, effectiveness, and safety we would expect of any other prescription drug. That standard has not yet been met.
	5.1 Traitements - Pré-clinique
'Breakthrough' breast cancer drug thwarted by chemical found in bread [The Telegraph] New research suggested the benefits of the “breakthrough” new drug palbociclib, which is given to women with oestrogen receptor-positive breast cancer, was effectively reversed by xenoestrogens.
Estrogen-mimicking compounds in foods may reduce effectiveness of breast cancer treatment [The Scripps] The study, published today in the journal Cell Chemical Biology, suggests that exposure to chemical compounds called xenoestrogens may significantly reduce the effectiveness of anti-estrogen treatments for cancer.
	5.2 Pharma
Pfizer oncology head Liz Barrett jumps ship to Novartis as Bruno Strigini steps aside [EndPoints] Barrett has big shoes to fill. The Swiss drugmaker has taken up a large presence in cancer since hiring Strigini — who’s says he’s retiring from the industry altogether — from a senior Merck position in the summer of 2014. Particularly memorable are its role in spearheading the first CAR-T to hit the market and the integration of GSK’s oncology portfolio.
	5.3 Traitements - FDA, EMA, NICE...
New study looks at FDA’s use of social media to communicate on drug safety [EndPoints] A new study looking at the FDA use of social media to communicate about drug safety finds that the agency could improve its impact by developing social media strategies and taking a more active role on web platforms.
	6. Lutte contre les cancers
Got a Great Research Idea? “All of Us” Wants to Hear It! [NIH Director's Blog] One of the boldest undertakings that NIH has ever attempted, the All of Us Research Program has been hard at work in a “beta” testing phase, and is now busy gearing up for full recruitment in the spring. This historic effort will enroll 1 million or more people in the United States to share information about their health, habits, and what it’s like where they live.
	6.1 Observation
BRCA gene mutation 'doesn't affect breast cancer survival' [BBC News] "Women diagnosed with early breast cancer who carry a BRCA mutation are often offered double mastectomies soon after their diagnosis or chemotherapy treatment. However, our findings suggest that this surgery does not have to be immediately undertaken along with the other treatment."
	6.11 Patients
Five things to remember after getting the dreaded cancer diagnosis [The Guardian] As if cancer treatment wasn’t trying enough, a common stress will be unwanted advice. But you can benefit from the wisdom of others.
	6.6 Publications
AACR Names Dr. Chi Van Dang as Editor-in-Chief of Cancer Research Journal [AACR] Dang is the scientific director of the Ludwig Institute for Cancer Research, an international, not-for-profit organization of distinguished scientists dedicated to preventing and controlling cancer. He is also a professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute in Philadelphia.
	6.8 Communication
‘What is cancer?’: Our answer to 2017’s most Googled health question [Cancer Research UK] Cancer Research UK sits among the top results, with a website dedicated to bringing readers the most accurate and up to date evidence-based information on the subject, from trials and treatments to pages sorting fact from fiction.