mercredi 6 décembre 2017

Onco Actu du 6 décembre 2017

1. Biologie

Adding Letters to the DNA Alphabet [NIH Director's Blog]

Everything You Need to Know About Crispr Gene Editing [Wired]

4.12 Biopsies liquides

Blood test could predict skin cancer's return [Cancer Research UK]

4.9 Dép., diag. & prono. - Sein

Seno Medical’s Imagio Combines Optoacoustics with Ultrasound to Diagnose Breast Cancer [medGadget]

Widespread screening for breast cancer didn't do much to save women's lives, study finds [LA Times]

5.1 Traitements - Pré-clinique

Combination Strategy Could Hold Promise for Ovarian Cancer [Johns Hopkins]

Breast, bowel and other cancers could be targeted by new drug type [Institute of Cancer Research]

A possible workaround for targeting the untargetable in a childhood nerve tumor [Broad Institute]

5.10 Traitements - Essais

Sanofi and J&J Lead the Way With Clinical Trial Transparency, Study Finds [RAPS]

5.12.4 Immunothérapies - Essais

U.S. Food and Drug Administration Lifts Partial Clinical Holds on Two Opdivo-based Combination Studies in Multiple Myeloma [BMS]

5.12.7 Immunothérapies - vaccins

New Immunotherapy for Deadly Childhood Brain Cancer Targets Novel “Neoantigen” [UCSF]

5.2 Pharma

Clovis Announces Priority Reveiw Designation for Rucaparib Supplemental New Drug Application [Clovis Oncology]]

Phase 3 Study Evaluating IMBRUVICA® (ibrutinib) in Combination with Rituximab in Waldenström’s Macroglobulinemia Met Primary Endpoint [Janssen]

5.2.3 Pharma - économie

Government and life sciences sector agree transformative sector deal [GOV.UK]

GSK welcomes launch of the UK Government’s Life Sciences Sector Deal [GSK]

5.3 Traitements - FDA, EMA, NICE...

Call for patient organisation representatives to join the Committee for Orphan Medicines [EMA]

EMA Issues Warning About Use of Radium-223 Dichloride in Combination With Abiraterone Acetate and Prednisone or Prednisolone [ESMO]

Merck and PhRMA to FDA: Wait for ICH before finalizing guidance on toxicity testing for cancer drugs [EndPoints]

FDA's program to speed up drug approval shaved nearly a year off the process [LA Times]

5.3.4 Traitements - AMM (FDA, EMA)

FDA Expands Use of Antibody–Drug Conjugate to Additional Types of Lymphoma [Cancer Research Catalyst]

5.4 Traitements - Economie

NICE says ‘no’ to Novartis’ AML drug Rydapt [PharmaTimes]

5.8.2 ASH - Pharma

AstraZeneca to highlight its commitment to blood cancers at the 2017 American Society of Hematology Annual Meeting [AstraZeneca]

6. Lutte contre les cancers

Veteran French pop singer Johnny Hallyday dies aged 74 after cancer battle [The Telegraph]

6.1 Observation

Consistently lower cancer survival rates for black patients in U.S. [Reuters]

6.10 Politiques

NHS cancer plan marks first step towards fixing chronic staff shortages [Cancer Research UK]

6.6 Publications

Hundreds of German universities set to lose access to Elsevier journals [Nature]

6.7 DMP, Big Data & applis

27 Top Breast Cancer Oncologists, Picked By Big Data [Forbes]