jeudi 21 décembre 2017

Onco Actu du 21 décembre 2017

2.6 Etiologie - Environnement

U.S. EPA says glyphosate not likely to be carcinogenic to people [Reuters]

3.1.1 Prévention - Tabac - e-cigs

Scientists describe problems in Philip Morris e-cigarette experiments [Reuters]

5. Traitements

The Antibody–Drug Conjugate Target Landscape [ESMO]

5.12 Immunothérapies

More Tumor Mutations Equals Higher Success Rate With Cancer Immunotherapy Drugs [Johns Hopkins]

5.12.1 Immunothérapies - partenariats

TARIS and Bristol-Myers Squibb Announce Clinical Trial Collaboration [BMS]

5.12.5 Immunothérapies - Pharma

Singapore’s Tessa raises $80M for T cell therapy push [FierceBiotech]

Parker Institute-allied Tessa grabs an $80M round for its next-gen cancer cell therapies [EndPoints]

5.12.6 Immunothérapies - AMM

Bristol-Myers Squibb Receives FDA Approval for Opdivo (nivolumab) as Adjuvant Therapy in Patients with Completely Resected Melanoma with Lymph Node Involvement or Metastatic Disease [BMS]

Oncology News Burst from FDA: Nivolumab [SITC]

5.12.8 Immunothérapies - Economie

Expensive new cancer therapy may be cost effective [Colorado Cancer Blogs]

Chimeric Antigen Receptor T-Cell Therapy for B-Cell Cancers: Effectiveness and Value [ICER]

5.2 Pharma

Bayer announces initiation of rolling submission of new drug application in the U.S. for larotrectinib for the treatment of TRK fusion cancers [Bayer]

5.2.3 Pharma - économie

Exelixis soars on blockbuster first-line nod for kidney cancer drug Cabometyx [FiercePharma]

GAO report tracks the growth of an $89B drug R&D sector as biopharma sales soared [EndPoints]

5.3.4 Traitements - AMM (FDA, EMA)

European Commission approves Roche’s Alecensa (alectinib) as first-line treatment in ALK-positive lung cancer [Roche]

FDA approves Roche’s Perjeta (pertuzumab) for adjuvant treatment of specific type of early breast cancer [Roche]

EU OKs first-line use of Roche’s lung cancer drug Alecensa [PharmaTimes]

Roche scores cancer drug approvals in Europe and U.S. [Reuters]

6. Lutte contre les cancers

2017 cancer research highlights: a patient’s pick [Cancer Research UK]

6.1 Observation

Many brain tumor patients do not receive adequate end-of-life care [Mass. General Hopsital]

Life expectancy in the U.S. is falling — and drug overdose deaths are soaring [STAT]

6.11 Patients

For better quality of life, older cancer patients need more than just medicine [Reuters]