jeudi 14 décembre 2017

Onco Actu du 14 décembre 2017

2.7 Etiologie - Obésité

Diabetes and obesity both tied to higher risk of cancer [Reuters]

3.1 Prévention - Tabac

Marijuana and Vaping Are More Popular Than Cigarettes Among Teenagers [NY Times]

4. Dépistage, diagnostic et pronostic

The Less-Is-More Crusade — Are We Overmedicalizing or Oversimplifying? [NEJM]

4.12 Biopsies liquides

New, simple blood tests for prostate cancer [Institute of Cancer Research]

5. Traitements

Building the clinical evidence on metformin and cancer [Cancer World]

5.12.1 Immunothérapies - partenariats

Bristol-Myers boosts I-O offering with new Ono drug deal [FierceBiotech]

Bristol-Myers Squibb Granted Exclusive License by Ono Pharmaceutical for Multiple Programs Targeting Immuno-Suppressive Factors in the Tumor Microenvironment [BMS]

5.12.3 Immunothérapies-combinaisons

New clues to boosting checkpoint inhibition in lung cancer [FierceBiotech]

5.12.5 Immunothérapies - Pharma

U.S. Food and Drug Administration (FDA) Accepts Bristol-Myers Squibb’s Application for Opdivo (nivolumab) Plus Yervoy (ipilimumab) in Intermediate- and Poor-Risk Patients with Advanced Renal Cell Carcinoma and Grants Priority Review [BMS]

Regeneron, Sanofi are ready to debut the 6th PD-1/L1. Is it still possible to stand out from the growing crowd? [EndPoints]

5.12.8 Immunothérapies - Economie

Pionyr Immunotherapeutics gains meaty $62M series B [FierceBiotech]

Yervoy inventor’s oncology startup Pionyr gets $62M for tumor-fighting tech [EndPoints]

5.2 Pharma

Eli Lilly builds $23B-plus sales forecast on diabetes, cancer launches [FiercePharma]

Sanofi faces a make-or-break year, saying it’s ready to put a 3-prong R&D strategy to a pivotal test [EndPoints]

5.2.1 Pharma - Partenariats

Daiichi Sankyo: Two steps forward, one step back in cancer deals [Pharmafile]

Daiichi ditches Nektar following cancer drug flop [EndPoints]

5.3.4 Traitements - AMM (FDA, EMA)

Bayer receives approval in China for Stivarga® (regorafenib) for the second-line systemic Treatment of liver cancer [Bayer]


First-line Ribociclib Improves PFS in Pre- and Peri-menopausal Women with HR-positive, HER2-negative Advanced Breast Cancer [ESMO]

5.8.4 ASH - CAR T

Preliminary Data from Servier and Pfizer’s UCART19 Product Candidate Shows High Complete Remission Rate Across Two Phase I Adult and Pediatric Acute Lymphoblastic Leukemia Trials [Cellectis]

6. Lutte contre les cancers

French researchers hope new chief will revitalize troubled funding agency [Nature]

6.1 Observation

Head and neck cancer survivors have long-lasting cognitive problem [Reuters]

6.11 Patients

Joe Biden Comforts Meghan McCain in Heartfelt Exchange on ‘The View’ [NY Times]

6.6 Publications

The science that’s never been cited [Nature]

6.7.2 Applis

Janssen Oncology rolls out, a website that's been years in the making [FiercePharma]

Janssen and Leading Advocacy Organizations Introduce, a Customizable Online Destination for People Impacted by Cancer [Johnson&Johnson]