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2. Etiologie
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2.8 Etiologie - Contraceptifs, THS
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3.1 Prévention - Tabac
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Austria to drop impending smoking ban, bucking Western trend [Reuters]
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Austria
passed a law banning smoking in bars and restaurants as of May 2018.
But that will now be overturned under a deal between the conservative
People’s Party (OVP) led by Sebastian Kurz and the far-right Freedom
Party (FPO) reached during their ongoing negotiations on a governing
coalition, according to a person familiar with their discussions.
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3.2 Prévention - Obésité
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Cancer and Obesity: Not Such a Linear Relationship [The ASCO Post]
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“BMI
may be useful at the population level, for surveillance, but with a
growing population of older, ethnically diverse cancer survivors, we are
going to need more precise measures of muscle and fat mass if we are
going to individualize supportive interventions.”
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4.5 Dép., diag. & prono. - Colorectal
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5. Traitements
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5.12.1 Immunothérapies - partenariats
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5.12.7 Immunothérapies - vaccins
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Gilead backs $60M Hookipa round to fund immunotherapy R&D [FierceBiotech]
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Vaxwave
is based on lymphocytic choriomeningitis virus. The twist is Hookipa
has replaced the gene encoding for a protein that enables the virus to
enter cells with one for the target antigen. Hookipa thinks the
resulting therapies will infect dendritic cells and stimulate immune
responses, without running the risk they will replicate and cause side
effects.
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5.2 Pharma
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Lilly Nixes Expansion of Stomach Cancer Drug After Mixed Study Results [Xconomy]
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Lilly
has already reported early data from a Phase 3 study showing that it
met its main goal of progression-free survival as a second-line bladder
cancer treatment. Overall survival data from that study are expected in
mid-2018. The Lilly drug is also in separate ongoing Phase 3 studies as a
treatment for cancers of the liver and the lung.
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5.3 Traitements - FDA, EMA, NICE...
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5.8 ASH
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Acupuncture in cancer study reignites debate about controversial technique [Nature]
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Oncologists
who conducted a trial of real and sham acupuncture in 226 women at 11
different cancer centres across the United States say their results —
presented on 7 December at the San Antonio Breast Cancer Symposium in
Texas — conclude that the treatment significantly reduces pain in women
receiving hormone therapy for breast cancer.
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5.8.1 ASH - Communiqués
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5.8.2 ASH - Pharma
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5.8.4 ASH - CAR T
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Bluebird and Celgene’s CAR-T hits the mark in myeloma [FierceBiotech]
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The
21-patient study showed an 86% overall response rate to the therapy,
which mobilizes the immune system to attack cancer cells expressing the
B-cell maturation antigen (BCMA). Moreover, all but one of 18 patients
on a higher dose of the CAR-T saw a clinical benefit, despite being very
ill with their disease progressing after a median of seven earlier
treatments.
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5.8.5 ASH - Myélome multiple
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5.8.6 ASH - Leucémies
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5.8.7 ASH - Lymphomes
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6. Lutte contre les cancers
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6.7.2 Applis
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