lundi 6 novembre 2017

Onco Actu du 6 novembre 2017

3.1 Prévention - Tabac

Regular smoking in young people at record low [Cancer Research UK]

4.2 Dép., diag. & prono. - Génome

Test could diagnose oesophageal cancer 8 years earlier [Cancer Research UK]

Deadly gullet cancer could be spotted eight years earlier with a new gene test [The Telegraph]

4.9 Dép., diag. & prono. - Sein

More breast cancer patients should be offered BRCA gene testing, new research shows [Institute of Cancer Research]

5. Traitements

Scientists exploit leaks in blood brain barrier to treat glioblastoma [Cancer Research UK]

The Drug Project Landscape [In the Pipeline]

Combined therapies increase adverse side effects for patients with advanced hormone receptor-positive breast cancer [RiceMason]

5.1 Traitements - Pré-clinique

Treating DNA Repair-deficient Breast Cancers [Cancer Research Catalyst]

PARP Inhibitor May Be Effective Against Some Triple-negative Breast Cancers Lacking BRCA Mutations [AACR]

5.10 Traitements - Essais

Younger women with advanced breast cancer needlessly excluded from treatment trials [RiceMason]

5.12 Immunothérapies

The battle between cancer and the immune system: who switches the off signals off? [University of York]

Hidden arm against tumors: microbiota-enabled checkpoint immunotherapy [NIHilist's Immunology]

5.12.2 Immunothérapies - CAR-T

Novartis reaches another regulatory milestone for CTL019 (tisagenlecleucel) with submission of its MAA* to EMA for children, young adults with r/r B-cell ALL and adult patients with r/r DLBCL [Novartis]

Novartis seeks European approval for cell therapy Kymriah [Reuters]

5.2.3 Pharma - économie

AbbVie Overpromises [Bloomberg]

5.3 Traitements - FDA, EMA, NICE...

Witty to head up new U.K. speedy drug/device review system [FierceBiotech]

Government unveils plans to accelerate access to medicine [PharmaTimes]

Government plan could see faster approvals for some promising new treatments [Cancer Research UK]

6. Lutte contre les cancers

NCRI 2017: World-class research on show in Liverpool [Institute of Cancer Research]

6.1 Observation

More women than men are diagnosed with bowel cancer as an emergency despite extra GP visits [Cancer Research UK]

Low testosterone levels linked to reduced risk of prostate cancer [Cancer Research UK]

6.6 Publications

Many Academics Are Eager to Publish in Worthless Journals [NY Times]