vendredi 20 octobre 2017

Onco Actu du 20 octobre 2017

1. Biologie

1 to 10 mutations are needed to drive cancer, scientists find [Sanger Institute]

'Handful of changes' make cancer [BBC News]

Thousands of studies could be flawed due to contaminated cells [NHS Choices]

Creative Minds: Using Machine Learning to Understand Genome Function [NIH Director's Blog]

2. Etiologie

A common herbal medicine may cause liver cancer mutations [New Scientist]

2.6 Etiologie - Environnement

In glyphosate review, WHO cancer agency edited out 'non-carcinogenic' findings [Reuters]

4.1 Dép., diag. & prono. - Prostate

EIT Innovators Award 2017 to prostate cancer screening project [Karolinska Institutet]

4.13 Dép., diag. & prono. - Peau

Pioneering imaging tech measures cell changes in melanoma [Institute of Cancer Research]

5.10 Traitements - Essais

Studies Identify Therapies That May Delay Melanoma Recurrence after Surgery [NCI]

5.12 Immunothérapies

Gene circuit switches on inside cancer cells, triggers immune attack [MIT News]

5.12.2 Immunothérapies - CAR-T

New gene-altering treatment offered for certain blood cancers [WUSTL]

5.2 Pharma

AstraZeneca EVP: Brexit is hindering our hiring [FierceBiotech]

5.2.3 Pharma - économie

Biosimilar threat starts to creep up on Roche as Rituxan loses ground [FiercePharma]

5.4 Traitements - Economie

Why doctor and hospital groups are fighting a measure to rein in drug costs [STAT]

Reframing the Conversation on Drug Pricing [NEJM Catalyst]

5.6 ESMO

Precision Medicine Experts Exploit Multiple Mutations to Improve Cancer Treatment [ESMO]

Cancer Outcome Depends on Complex Interactions Between Many Mutations [ESMO]

6. Lutte contre les cancers

England’s cancer strategy: what has changed in the last two years? [Cancer Research UK]

Sean Parker’s cancer institute keeps growing with some “mind blowing” new research projects [EndPoints]

6.1 Observation

Oral Sex and Smoking Increase Men’s Risk of Head and Neck Cancer But the Risk is Still Low, Making Screening for the Disease a Challenge [ESMO]

6.11 Patients

New Patient Guidelines from the National Comprehensive Cancer Network Offer Much-Needed Clarity around a Group of Rare Blood Cancers [NCCN]

6.7 DMP, Big Data & applis

Data privacy in the age of big data [EMA]