mercredi 18 octobre 2017

Onco Actu du 18 octobre 2017

1. Biologie

GA4GH Strikes Formal Collaborations with 15 International Genomic Data Initiatives [GA4GH]

3.1 Prévention - Tabac

Study estimates the scale and growth potential of heat-not-burn cigarettes [Stanford Medicine]

World Bank says ‘go big, go fast’ to stub out tobacco [Financial Times]

4. Dépistage, diagnostic et pronostic

Scientists Led by Mount Sinai and Sema4 Identify Biomarker for Progression and Drug Response in Brain Cancer [Mouint Sinai Hospital]

4.2 Dép., diag. & prono. - Génome

Ultra-personal therapy: Gene tumor boards guide cancer care [AP]

How to Spend $1,900 on Gene Tests Without Learning a Thing [MIT Technology Review]

4.9 Dép., diag. & prono. - Sein

AI used to detect breast cancer risk [BBC News]

5. Traitements

Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development: Proceedings of a Workshop (2017) [NAP]

Personalised treatments for rare cancers tested in study [Cancer Research UK]

5.12.7 Immunothérapies - vaccins

Despite notable failures, cancer vaccines are poised for a leap onto the market: expert [FiercePharma]

5.13 WCLC

Biopsy Specimen found to be Reliable for Evaluating DLL3 Expression in Small Cell Lung Cancer [IASLC]

Researchers Confirm IASLC Proposed Characterization of Uncertain R Status R(un), with Prognosis Between R0 and R1 [IASLC]

Tiny Ignyta's Lung Cancer Drug Bested Pfizer's. Probably. Will We Ever Know For Sure? [Forbes]

Early Palliative Care Provides No Additional Quality of Life Benefits for Recently Diagnosed Malignant Pleural Mesothelioma (MPM) Patients [IASLC]

5.2 Pharma

US FDA accepts regulatory submission for Lynparza in metastatic breast cancer and grants Priority Review [AstraZeneca]

Astra and Merck win speedy review for Lynparza in breast cancer [Reuters]

5.2.3 Pharma - économie

Johnson & Johnson drops sirukumab after FDA blow, cans phase 3 AML trial [FierceBiotech]

New cancer drugs help Johnson & Johnson top profit estimates [Reuters]

5.3 Traitements - FDA, EMA, NICE...

Responses to the comments from EMA [BMJ]

6. Lutte contre les cancers

Flu vaccine failed to protect young leukemia patients during cancer treatment [St. Jude Children's Research Hospital]

6.6 Publications

Who’s the most influential biomedical scientist? Computer program guided by artificial intelligence says it knows [Science]

6.9 Controverses

J&J prevails in first talc appeal as judges vacate $72M verdict [FiercePharma]

Johnson & Johnson wins reversal of $72 million verdict over talc cancer risks [Reuters]