vendredi 13 octobre 2017

Onco Actu du 13 octobre 2017

1. Biologie

Exploring the Role of Metabolism in Cancer [Cancer Research Catalyst]

Scientists pinpoint surprising origin of melanoma [VIB]

2. Etiologie

5 persistent myths about the causes of breast cancer [Cancer Research UK]

3.1 Prévention - Tabac

Higher cigarette pricing encourages older smokers to quit [CA]

4.11 Dép., diag. & prono. - Ovaire

Immune response to ovarian cancer may predict survival [USNW]

4.12 Biopsies liquides

Liquid biopsy could lead to precision therapies for children’s eye tumors [STAT]

A liquid biopsy for retinoblastoma [Children's Hospital LA]

5. Traitements

New drug hope for patients with rare bone cancer [Sanger Institute]

5.1 Traitements - Pré-clinique

Johns Hopkins Scientists Develop Experimental “Nano-Chemo” Particle to Treat Bladder Cancer [Johns Hopkins]

5.12.1 Immunothérapies - partenariats

NIH allies with 11 top cancer biopharma players in $215M drive to explore biomarkers, speed R&D [EndPoints]

U.S. NIH, 11 drugmakers partner to accelerate cancer therapy research [Reuters]

NIH partners with 11 leading biopharmaceutical companies to accelerate the development of new cancer immunotherapy strategies for more patients [NIH]

To accelerate new cancer treatments, NIH will team up with pharma on immunotherapy research [STAT]

5.12.2 Immunothérapies - CAR-T

Averting toxic side effects from CAR-T cancer treatments [FierceBiotech]

Biomarkers may help identify patients at increased risk of neurotoxicity from CD19 CAR T-cell therapy [ecancernews]

5.2 Pharma

J&J takes another big step forward with next-gen prostate cancer blockbuster apalutamide [EndPoints]

5.2.3 Pharma - économie

A Bit About Biopharma Investing [In the Pipeline]

Medicxi kickstarts a new cancer drug developer with $19M launch round [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

European drug regulation at risk of stalling as agency prepares to leave London [Nature]

5.3.4 Traitements - AMM (FDA, EMA)

Pembrolizumab Secures FDA Approval in Stomach Cancer [NCI]

5.4 Traitements - Economie

NICE expands Bayer's Stivarga prospects with move from CDF [FiercePharma]

NICE gives final draft guidance on two key cancer drugs [Pharmafile]

We may soon have our first $1 million drug. Who will pay for it? And how? [STAT]

6. Lutte contre les cancers

Curing cancer isn't always the goal. Sometimes you just want it to be a manageable chronic disease [LA Times]

6.10.1 Politiques (USA)

Health Insurance Rule Threatens Key Component of Standard Cancer Treatment [ASCO]

6.11 Patients

'If it's not normal for you, get it checked' [BBC News]

Living With Cancer: Cancer Humor [NY Times]