mardi 26 septembre 2017

Onco Actu du 26 septembre 2017

1. Biologie

Tumor Microenvironment of Triple Negative Breast Cancer Varies Between African-American Women and European-American Women [AACR]

4.9 Dép., diag. & prono. - Sein

MRI contrast agent locates and distinguishes aggressive from slow-growing breast cancer [Case Western]

5.10 Traitements - Essais

Ethnic Minorities and the Elderly Are Underrepresented in Cancer Clinical Trials [AACR]

5.12 Immunothérapies

Immunotherapy has changed cancer medicine. But it's no miracle cure [The Guardian]

5.12.1 Immunothérapies - partenariats

AstraZeneca, NewLink pen PD-L1 and IDO combination pact [FierceBiotech]

NewLink Genetics Announces Clinical Collaboration to Evaluate IO-Based Combination Therapies in Pancreatic Cancer [NewLink]

5.12.5 Immunothérapies - Pharma

Amid Cash Crunch, Genocea to Dump Herpes Vaccine, Focus on Cancer Work [Xconomy]

5.12.6 Immunothérapies - AMM

Bristol-Myers' I-O star Opdivo steps up to challenge Bayer's Stivarga in liver cancer [FiercePharma]

5.2.3 Pharma - économie

Pfizer launches upstart with $103M, phase 3-ready drugs [FierceBiotech]

Pfizer sets up its own biotech to develop rejected drugs [Pharmafile]

Pfizer spends billions to develop new drugs. It’s not satisfied. So it’s launching a startup [STAT]

Pfizer Channels Its Inner Biotech [Bloomberg]

Pfizer spins off drug orphans into a PhIII-ready startup backed by Bain to the tune of $103M [EndPoints]

5.4 Traitements - Economie

Everyone says we’ve got to rein in drug prices. So why don’t we? [STAT]

5.9.1 ASTRO

Phase III trial confirms pelvic radiation as standard of care for high-risk, early-stage endometrial cancer [ASTRO]

Aggressively reduced radiation therapy for HPV-related throat cancer achieves similar control rates with fewer side effects [ASTRO]

Accelerated breast radiation therapy following mastectomy shortens treatment time while maintaining tumor control [ASTRO]

Immune response prognostic for prostate cancer survival, recurrence and response to radiation therapy [ASTRO]

Long-term survival rates more than double previous estimates for locally advanced lung cance [ASTRO]

Biomarker blood test predicts survival following localized lung cancer treatment [ASTRO]

Adding radiation to chemotherapy may dramatically improve survival for advanced-stage NSCLC patients [ASTRO]

Radiation-immunotherapy combination can slow tumor growth for some patients with metastatic late-stage cancer [ASTRO]

International trial confirms safety, effectiveness of high-dose brachytherapy plus pelvic radiation for cervical cancer [ASTRO]

6. Lutte contre les cancers

Breast surgeons exert 'enormous influence' on patients’ choices [Reuters]

Studying 1 million people to end cookie-cutter health care [AP]

6.11 Patients

I Treated Breast Cancer for Years as a Doctor. Then I Was Diagnosed [Time]

6.4 Médico-éco

Three ways to make proton therapy affordable [Nature]

6.5 Médecines alternatives

Rigvir: A cancer “cure” imported from Latvia that cancer patients should avoid [Respectful Insolence]