jeudi 6 juillet 2017

Onco Actu du 6 juillet 2017

1. Biologie

Genomic analysis of key acute leukemia will likely yield new therapies [St. Jude Children's Hospital]

Spreading cancer caught on film [BBC News]

3.1.1 Tabac - e-cigs

Effectiveness of fire-safe cigarette laws still unclear [Reuters]

4. Dépistage, diagnostic et pronostic

Tumor Scanner Promises Fast 3D Imaging of Biopsies [NIH Director's Blog]

4.12 Biopsies liquides

Angle’s ovarian cancer test could beat current standard [PharmaTimes]

5. Traitements

Chemotherapy may spread cancer and trigger more aggressive tumours, warn scientists [The Telegraph]

5.12.1 Immunothérapies - partenariats

Celgene Corporation Enters Into Global Strategic Immuno-Oncology Collaboration with BeiGene to Advance PD-1 Inhibitor Program for Solid Tumor Cancers [Celgene]

Celgene to buy BeiGene stake, to develop tumor cancer treatment [Reuters]

5.12.3 Immunothérapies-combinaisons

Noxxon Pharma Announces First Patients Treated in Pase I/II Clinical Trial or Nox-A12 Combined with Keytruda in Metastatic and Colorectal Cancer [Noxxon]

5.12.4 Immunothérapies - Essais

Merck Provides Further Update on Three Multiple Myeloma Studies Evaluating KEYTRUDA® (pembrolizumab) in Combination with Pomalidomide or Lenalidomide [Merck]

FDA Halts Merck’s Multiple Myeloma Trials After Patient Deaths [Xconomy]

Troubled by deaths, FDA orders Merck to slam the brakes on three Keytruda studies [EndPoints]

FDA puts hold on Merck multiple myeloma trials after deaths [Reuters]

5.12.5 Immunothérapies - Pharma

Oxford BioMedica wins big contract for Novartis cell therapy [Reuters]

Phase 3 Study Evaluating the Safety and Efficacy of Adjuvant Opdivo in Resected High-Risk Melanoma Patients Meets Primary Endpoint [BMS]

Bristol-Myers’ tarnished checkpoint star Opdivo beats out Yervoy in surprise PhIII [EndPoints]

5.12.7 Immunothérapies - vaccins

Personalized cancer vaccines stake their claim to the next frontier in immuno-oncology [EndPoints]

Personalized Cancer Vaccines Look Promising in Two New Studies [MIT Technology Review]

Personalized cancer vaccines vanquish melanoma in small but encouraging study [STAT]

Personalized cancer vaccines show glimmers of success [Nature]

Personalized vaccines hold cancer at bay in two early trials [Reuters]

5.2 Pharma

Array BioPharma Submits New Drug Applications To FDA For Binimetinib And Encorafenib In Advanced Melanoma [Array]

5.3 Traitements - FDA, EMA, NICE...

Researchers Find Most Expert Speakers at FDA ODAC Meetings Receive Sizable Industry Payments [RAPS]

5.5 ASCO

Making a Difference in Cancer Care With You [JCO]

6.13 Soins palliatifs

Health Affairs’ July Issue: Advanced Illness & End-Of-Life Care [Health Affairs]

6.6 Publications

Variations in Databases Used to Assess Academic Output and Citation Impact [NEJM]

6.8 Communication

A newspaper’s murky partnership with a regional oncology center: boosting revenue but misleading readers [HealthNewsReview]

6.9 Controverses

French scientist fined for failure to disclose industry ties [Nature]