lundi 17 juillet 2017

Onco Actu du 17 juillet 2017

2. Etiologie

Rogue chromosome may be behind new contagious cancer striking Tasmanian devils [Science]

2.6 Etiologie - Environnement

Does the World’s Top Weed Killer Cause Cancer? Trump’s EPA Will Decide [Bloomberg]

3.1 Tabac

Inside Philip Morris’ campaign to subvert the global anti-smoking treaty [Reuters]

The Guardian view on big tobacco: stop the spread [The Guardian]

Tobacco Gets More Screen Time in Blockbuster Movies, Study Shows [NY Times]

Tobacco companies tighten hold on Washington under Trump [The Guardian]

3.8 Prévention - Alimentation

Coffee & sleep stories mostly miss the association ≠ causation emphasis [HealthNewsReview]

4.7 Dép., diag. & prono. - Col de l'utérus

Accidental effect of fewer Pap screenings: more cases of undiagnosed chlamydia [STAT]

4.9 Dép., diag. & prono. - Sein

MammaPrint Test Addressed in ASCO Breast Cancer Guideline Update [ASCO]

5. Traitements

Chemotherapy before breast cancer surgery might fuel metastasis [STAT]

Does chemotherapy cause cancer to spread? [Science-Based Medicine]

Long-term, surgery for localized prostate cancer offers little extra benefit [Reuters]

A stem cell transplant helped beat back a young doctor’s cancer. Now, it’s assaulting his body [Science]

Converging on cancer at the nanoscale [MIT News]

MTH1: From Hot Topic to Devalidation? [In the Pipeline]

5.10 Traitements - Essais

NCI-MATCH keeps enrolling—Targeted mutations are proving to be less common than estimated [The Cancer Letter]

5.12 Immunothérapies

Cord blood inspires an alternative to CAR-T for treating blood cancers [FierceBiotech]

5.12.2 Immunothérapies - CAR-T

Novartis CAR-T cell therapy CTL019 unanimously (10-0) recommended for approval by FDA advisory committee to treat pediatric, young adult r/r B-cell ALL [Novartis]

CAR-Ts Clear One Roadblock But Face Many More [Bloomberg]

Panel Backs CAR T-cell Therapy for Leukemia: What You Need to Know and What’s Next [ACS]

Unanimous Advice To FDA: Approve Landmark CAR-T Cancer Therapy [Xconomy]

Novartis CAR-T cancer therapy wins expert support for FDA approval [STAT]

'Living Drug' That Fights Cancer By Harnessing Immune System Clears Key Hurdle [NPR]

F.D.A. Panel Recommends Approval for Gene-Altering Leukemia Treatment [NY Times]

Engineered cell therapy for cancer gets thumbs up from FDA advisers [Nature]

FDA advisers back Novartis’ game-changing personalized CAR-T for cancer, approval in sight [EndPoints]

FDA panel backs Novartis' pioneering new cancer gene therapy [Reuters]

5.12.3 Immunothérapies-combinaisons

Exelixis and Bristol-Myers Squibb Initiate Phase 3 Trial of Opdivo® in Combination with CABOMETYX™ or Opdivo and Yervoy® in Combination with CABOMETYX, Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma [BMS]

5.12.6 Immunothérapies - AMM

FDA Considers Label Changes for Keytruda, Opdivo and Yervoy [RAPS]

5.2 Pharma

Chaos at AstraZeneca [in the Pipeline]

Pascal Soriot is staying at AstraZeneca after all, confirming upcoming presentation – reports [EndPoints]

U.S. Food and Drug Administration Accepts for Priority Review Bristol-Myers Squibb’s Application for Sprycel (dasatinib) in Children with Philadelphia Chromosome-Positive Chronic Phase Chronic Myeloid Leukemia [BMS]

Fact-checking pharma: 5 cancer drug myths, busted [HealthNewsReview]

5.3 Traitements - FDA, EMA, NICE...

Two Recent Scientific Advances Underscore an Encouraging Future for Precision Medicine at FDA [FDA Voice]

5.3.4 Traitements - AMM (FDA, EMA)

New Rituximab Formulation Approved for Some Lymphomas, Leukemia [NCI]

5.4 Traitements - Economie

A new treatment option for people with kidney cancer [NICE]

Kidney cancer drug approved for NHS use in England [BBC News]

Drug industry to challenge Nice over new cost limits [BBC News]

6.1 Observation

Cancer Research UK comments on the Government's response to the National Data Guardian Review [Cancer Research UK]

Tall men at bigger risk of aggressive prostate cancer, study suggests [The Guardian]

Lung and colon cancer more likely to strike survivors of persecution [Reuters]

Cancer diagnosis 'more common than marriage' [BBC News]

6.10.1 Politiques (USA)

ASCO Remains Opposed to Senate Healthcare Bill, Urges Protections for Access to High-Quality Care [ASCO]

US lawmakers seek $1.1-billion boost for the NIH [Nature]

6.11 Patients

A new way to organize cancer support groups: A caregivers’ suggestion [Stanford Medicine]

15 percent of men regret prostate cancer treatment choices years later, study finds [STAT]

6.6 Publications

MIT convenes ad hoc task force on open access to Institute’s research [MIT News]

Biology's Rolling Debate Over Publishing Research Early [Wired]

6.7 DMP, Big Data & applis

Training Complete, ONS CancerLinQ Ambassadors Prepare to Help Practices Launch Big Data Platform to Support Value and Evidence-Based Health Care [ASCO]