jeudi 29 juin 2017

Onco Actu du 29 juin 2017

1. Biologie

The breast cancer genome’s “dark matter” starts to give up some secrets [Broad Institute]

3.3 Prévention - Vaccins

Vaccine ruling from Europe's highest court isn't as crazy as scientists think [Nature]

4. Dépistage, diagnostic et pronostic

A New Optical System Can Detect Cancer in Real Time With High Accuracy During Surgery [AACR]

Fibre-optic device can detect stray cancer cells, improve tumour removal: study [Globe and Mail]

4.10 Dép., diag. & prono. - Poumon

Cancer Genetics, Inc. Launches FDA-Approved Universal Companion Diagnostic for Lung Cancer Leveraging Thermo Fisher's Next Generation Sequencing Panel Oncomine Dx Target Test [Cancer Genetics]

4.2 Dép., diag. & prono. - Génome

Aiming for clarity in cancer gene testing, researchers at Stanford and Fox Chase turn to big data [Stanford Medicine]

5.12 Immunothérapies

Barrier Proteins in Tumors are Possible Key to Immunotherapy Success [Johns Hopkins]

5.2 Pharma

Before Iclusig safety flaws went public, ex-Ariad staffer told family to sell shares: feds [FiercePharma]

5.2.1 Pharma - Partenariats

AstraZeneca, Chi-Med take kidney cancer drug into final testing [Reuters]

CRT’s Discovery Laboratories extends alliance with Merck to develop new cancer drugs [Cancer Research UK]

5.2.3 Pharma - économie

Vivace uncloaks with $40M, U.S.-China backing for cancer trials [FierceBiotech]

Vivace Therapeutics Comes Out of Stealth With $25M for Cancer Drugs [Xconomy]

With deep ties to China, Vivace exits stealth mode with a lead cancer program, platform and $40M [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

FDA-AACR Regulatory Science and Policy Workshop [AACR]

5.3.4 Traitements - AMM (FDA, EMA)

Novartis receives EU approval for first-line use of Zykadia® in ALK-positive advanced non-small cell lung cancer (NSCLC) [Novartis]

5.4 Traitements - Economie

NICE backs Afinitor, Sutent for neuroendocrine tumours [PharmaTimes]

5.6 ESMO

Halozyme Phase 2 Data In Advanced Pancreas Cancer Presented At European Society For Medical Oncology Symposium [Halozyme]

6. Lutte contre les cancers

Quality and collaboration, not growth, should drive research institutions [STAT]

6.1 Observation

Differences and Disparities in Cancer [Cancer Research Catalyst]

6.6 Publications

Image doctoring must be halted [Nature]

6.7 DMP, Big Data & applis

Dr. Robert Califf Shares Ideas About Real-World Evidence And Health Data [Forbes]

6.7.3 DMP

Without Interoperability, EHRs Are Too Expensive [HIT Consultant]