mardi 20 juin 2017

Onco Actu du 20 juin 2017

1. Biologie

Researchers Develop Human Tissue Platform to Test Drugs for Colon Cancer [Oncology Times]

2.5 Etiologie - Gènes

More thoughts, and just plain provocateuring, on genomic causal complexity. . . . [The Mermaid's Tale]

Omnigenic drug discovery [PLENGE GEN]

3.1.1 Tabac - e-cigs

Occasional smokers who vape smoke more cigarettes [Reuters]

4. Dépistage, diagnostic et pronostic

Giles Maskell: The practice of radiology needs to change [BMJ Blogs]

4.12 Biopsies liquides

Blood test may show if prostate cancer treatment is working [NHS Choices]

4.2 Dép., diag. & prono. - Génome

Catalyzing Integration of Genomic and Clinical Datasets Across Multiple Cancer Institutions Worldwide [ESMO]

5. Traitements

Surgery and High-Dose SBRT Radiation Can Be Combined to Treat Kidney Cancer, Roswell Park Researchers Show [Roswell Park Cancer Institute]

Immune Cells Deliver Cancer Drugs to the Brain [The Scientist]

Bedside drug production will truly enable personalized medicine [STAT]

5.10 Traitements - Essais

Three-Year Follow-Up Data Showed Patients Achieved Four-Fold Progression-Free Survival Benefit with Single Agent Imbruvica®▼ (ibrutinib) vs Temsirolimus at First Relapse in Mantle Cell Lymphoma [Janssen]

5.12 Immunothérapies

Discovery could guide immunotherapy for lung cancer [Cancer Research UK]

Scientists find new biomarker to guide cancer immunotherapy [Reuters]

5.12.1 Immunothérapies - partenariats

Parker-Tessa alliance tees up solid tumor I-O combinations [FierceBiotech]

5.2 Pharma

Seattle Genetics stops all trials of '33A blood cancer drug after patient deaths [FierceBiotech]

SeaGen Ends One Leukemia Drug Trial, Stops Enrolling Three Others [Xconomy]

Slammed by more deaths, Seattle Genetics scraps a PhIII study and pulls back (again) on vadastuximab [EndPoints]

Seattle Genetics Discontinues Phase 3 CASCADE Trial of Vadastuximab Talirine (SGN-CD33A) in Frontline Acute Myeloid Leukemia [Seattle Genetics]

Seattle Genetics halts late-stage study of leukemia drug [Reuters]

5.2.3 Pharma - économie

Current biopharma R&D costs ‘unsustainable’, warns report [PharmaTimes]

5.4 Traitements - Economie

The Future of Oncology Treatment and Value Assessment [Healthcare Economist]

5.5 ASCO

ASCO 2017: 4 ways treatment could change following world’s largest cancer conference [Cancer Research UK]

5.5.3 ASCO (prostate)

Abiraterone Improves Survival for Some Men with Hormone-Sensitive Prostate Cancer [NCI]

6. Lutte contre les cancers

Long-term Survivorship Care after Cancer Treatment: A Workshop [National Academies]

Results are in for Europe’s First Biobanking Study on HPV Cervical Cancer []

‘Human Project’ study will ask 10,000 to share life’s data [STAT]

6.10 Politiques

Macron consolidates electoral victory [Nature]

6.10.1 Politiques (USA)

If drug companies are really ‘getting away with murder,’ Trump may be about to grant them a pardon [STAT]

6.6 Publications

Microsoft Academic is on the verge of becoming a bibliometric superpower [LSE Impact Blog]

6.7 DMP, Big Data & applis

Apple is working with this small start-up to change how we track our health [CNBC]