mercredi 31 mai 2017

Onco Actu du 31 mai 2017

1. Biologie

Possible target for treating breast cancer that’s spread to brain found in mice [Cancer Research UK]

3.1 Tabac

Big tobacco leaves huge ecological footprint - WHO [Reuters]

3.1.1 Tabac - e-cigs

Move over Hippocrates: Harm reduction as the new paradigm for health care [STAT]

5.12 Immunothérapies

Immunotherapy: 'Revolutionary' new treatment made available to lung cancer patients on NHS for first time [Independent]

5.12.1 Immunothérapies - partenariats

Array BioPharma and Bristol-Myers Squibb Announce Strategic Collaboration [BMS]

Advaxis and Bristol-Myers Squibb Announce Clinical Collaboration to Evaluate ADXS-DUAL and Opdivo (nivolumab) in Metastatic Cervical Cancer [BMS]

Bristol-Myers Hookup Boosts Array BioPharma [The Street]

Bristol-Myers Squibb adds to its roster of checkpoint combo studies, partnering with Array and Advaxis [EndPoints]

5.12.2 Immunothérapies - CAR-T

Novartis next generation CAR-T cell therapy CTL119 combined with ibrutinib shows high rate of responses in CLL patients [Novartis]

Novartis isn’t messing around with CAR-T, and it has a next-gen therapy to help prove it [EndPoints]

5.12.3 Immunothérapies-combinaisons

On ASCO’s Eve, Experts Fret Over Backlash to Cancer Combo Frenzy [Xconomy]

5.2.1 Pharma - Partenariats

Sanofi beefs up cancer drug pipeline, paying cash hungry ImmunoGen $30M for full rights to oncology portfolio [EndPoints]

ImmunoGen gets $30M amid Sanofi ADC deal shake-up [FierceBiotech]

5.3.4 Traitements - AMM (FDA, EMA)

Novartis' Zykadia piles pressure on Pfizer's Xalkori, Roche's Alecensa with new lung cancer nod [FiercePharma]

New FDA Approval for Zykadia (ceritinib) for ALK-Positive NSCLC: Why I Think It’s a Poor Choice for Initial Treatment [Cancer Grace]

5.5 ASCO

Prepping for ASCO? Investor Brad Loncar offers his own breakdown of what to watch for [EndPoints]

5.5.4 ASCO (immunothérapies)

Triple immunotherapy for rare skin cancer shows promise in small, early-stage trial [Fred Hutch]

6. Lutte contre les cancers

Last month in Oncology with Dr. Bishal Gyawali: May 2017 [ecancernews]

6.10.1 Politiques (USA)

AACR Strongly Opposes President Trump’s Fiscal Year 2018 Budget Proposal for the NIH [AACR]

Ryan appoints controversial cancer doctor to HHS committee [Politico]

6.6 Publications

BMJ journal yanks paper on cancer screening in India for fear of legal action [Retraction Watch]

Crowd-based peer review can be good and fast [Nature]

How Much Citation Manipulation Is Acceptable? [The Scholarly Kitchen]