vendredi 12 mai 2017

Onco Actu du 12 mai 2017

1. Biologie

Snapshots of Life: Biological Bubble Machine [NIH Director's Blog]

3.1 Tabac

Cutting smoking rates could save the NHS £67 million a year [Cancer Research UK]

4. Dépistage, diagnostic et pronostic

Human Longevity, Inc. Launches Pilot Program, Health Nucleus X [Human Longevity]

4.1 Dép., diag. & prono. - Prostate

Cleveland Clinic-led Study Finds That New Blood Test is More Accurate in Predicting Overall Risk of Prostate Cancer than Standard Prostate-Specific Antigen (PSA) [Cleveland Clinic]

4.12 Biopsies liquides

Guardant Health Raises $350 Million In Race To Create Cancer Blood Tests [Forbes]

4.5 Dép., diag. & prono. - Colorectal

NHS patients waiting months for vital bowel cancer tests, figures show [The Guardian]

5. Traitements

Human Antibody Discovery: Of Mice And Phage [Life Sci VC]

5.12 Immunothérapies

Molecular imaging reveals mechanism for resistance to immune checkpoint blockade [Mass General Hospital]

5.12.5 Immunothérapies - Pharma

Imfinzi significantly reduces the risk of disease worsening or death in the Phase III PACIFIC trial for Stage III unresectable lung cancer [AstraZeneca]

Key AstraZeneca drug shown to reduce risk of death from lung cancer [Reuters]

5.12.6 Immunothérapies - AMM

Merck Immunotherapy Drug Notches Another FDA Win in Lung Cancer [Xconomy]

Merck Can't Say How Good its Good News Is [Bloomberg]

FDA Approves Combining Merck’s Keytruda With Chemotherapy in Lung Cancer Patients [Wall Street Journal]

Has Merck Lucked Into A $10 Billion Drug? [Forbes]

5.2 Pharma

Array BioPharma Announces Positive Top-Line Results from Part 2 of the Phase 3 COLUMBUS Study of Binimetinib and Encorafenib for BRAF-Mutant Melanoma [Array]

Array shares surge as second chapter of its PhIII cancer combo story ends on an upbeat note [EndPoints]

5.4 Traitements - Economie

WHO wants transparency, market revamp for fairer drug pricing [Reuters]

6. Lutte contre les cancers

Changes in NIH Grant Policy? [In the Pipeline]

6.10 Politiques

China cracks down on fake data in drug trials [Nature]

6.4 Médico-éco

Breast cancer treatment costs higher for younger women [Reuters]

6.6 Publications

Paper by Harvard cancer biologist flagged over “credible concerns” [Retraction Watch]

“Dramatic impact:” Authors misread breast cancer treatment database, retract paper [Retraction Watch]

6.7.1 Bioinformatique

Using AI to Detect Cancer, Not Just Cats [Wired]

6.8 Communication

Why we should all be wary when PR machines promote phase 2 studies [healthNewsReview]