|
1. Biologie
|
|
|
Snapshots of Life: Biological Bubble Machine [NIH Director's Blog]
|
|
|
|
|
|
Until
recently, most efforts to exploit vesicles for therapeutic uses have
employed synthetic versions of a different type of vesicle, called an
exosome. But Stachowiak and others have realized that PMVs come with
certain built-in advantages. A major one is that a patient’s own cells
could in theory serve as the production facility.
|
|
|
|
|
|
|
3.1 Tabac
|
|
|
|
4. Dépistage, diagnostic et pronostic
|
|
|
|
|
4.1 Dép., diag. & prono. - Prostate
|
|
|
|
4.12 Biopsies liquides
|
|
|
|
4.5 Dép., diag. & prono. - Colorectal
|
|
|
|
5. Traitements
|
|
|
Human Antibody Discovery: Of Mice And Phage [Life Sci VC]
|
|
|
|
|
|
Instead
of worrying about “can I make a potent antibody”, the focus for most
researchers has shifted to “will a potent antibody deliver value to
patients”. This latter question is where most antibodies, if they fail,
come a part in the clinic these days: disease biology is hard to fully
appreciate until you do the clinical work.
|
|
|
|
|
|
|
5.12 Immunothérapies
|
|
|
|
5.12.5 Immunothérapies - Pharma
|
|
|
|
|
5.12.6 Immunothérapies - AMM
|
|
|
|
Merck Can't Say How Good its Good News Is [Bloomberg]
|
|
|
|
|
|
Merck
is now firmly leading the lung-cancer market, and arguably the IO
market in general. But it knows how quickly fortunes can change.
Bristol-Myers was seen as leading the pack comfortably until Opdivo
failed an aggressive trial in newly diagnosed lung-cancer patients,
where Keytruda is succeeding.
|
|
|
|
|
|
|
|
|
5.2 Pharma
|
|
|
|
|
5.4 Traitements - Economie
|
|
|
|
6. Lutte contre les cancers
|
|
|
Changes in NIH Grant Policy? [In the Pipeline]
|
|
|
|
|
|
The
NIH is completely within its rights (and in fact, its responsibilities)
to keep an eye on how its grants are evaluated and awarded. But this
proposal seems arbitrary and disingenuous, a good shot at getting the
worst of both worlds.
|
|
|
|
|
|
|
6.10 Politiques
|
|
|
|
6.4 Médico-éco
|
|
|
|
6.6 Publications
|
|
|
|
|
6.7.1 Bioinformatique
|
|
|
Using AI to Detect Cancer, Not Just Cats [Wired]
|
|
|
|
|
|
Just
as a neural network can identify a cat in a snapshot of your living
room, it can identify tiny aneurysms in eye scans or pinpoint nodules in
CT scans of the lungs. Basically, after analyzing thousands of images
that contain such nodules, it can learn to identify them on its own.
|
|
|
|
|
|
|
6.8 Communication
|
|
|