mercredi 10 mai 2017

Onco Actu du 10 mai 2017

1. Biologie

Parkinson’s gene mutation discovered in one third of cancers [Institute of Cancer Research]

4.14 Dép., diag. & prono. - Thyroïde

Don't Screen For Thyroid Cancer, Task Force Says [NPR]

5. Traitements

Combination treatment for advanced lung cancer does not improve survival [ecancernews]

5.10 Traitements - Essais

Roche provides update on phase III study of TECENTRIQ® (atezolizumab) in people with previously treated advanced bladder cancer [Roche]

Roche's Tecentriq fails trial in advanced bladder cancer [Reuters]

5.12 Immunothérapies

The Progress of Cancer Immunotherapy: The Tip of the Iceberg [Dana-Farber Cancer Institute]

5.12.2 Immunothérapies - CAR-T

After Kite Pharma stuns analysts with news of a death in lead CAR-T study, safety questions sour launch forecast [EndPoints]

5.12.5 Immunothérapies - Pharma

Soon-Shiong's I-O outfits get FDA nod to start cancer vaccine trials [FierceBiotech]

Servier and Pfizer announce FDA clearance of IND application for UCART19 in Adult Relapsed/Refractory Acute Lymphoblastic Leukemia [Cellectis]

5.12.6 Immunothérapies - AMM

FDA grants accelerated approval to avelumab for urothelial carcinoma [FDA]

Move over, AstraZeneca. Pfizer and Merck KGaA are the newest bladder cancer drugmakers in town [FiercePharma]

Pfizer immuno-oncology drug wins U.S. approval for bladder cancer [Reuters]

5.3 Traitements - FDA, EMA, NICE...

Senate Vote Confirms Scott Gottlieb for FDA Commissioner [Xconomy]

Trump wants faster FDA action, but 1 in 3 drugs have safety issues after approval [STAT]

Scott Gottlieb wins confirmation as FDA commissioner [STAT]

It’s official: Senate confirms Scott Gottlieb as the country’s next FDA commissioner [EndPoints]

6. Lutte contre les cancers

‘Death and dying continues to be seen as a big taboo’ [The Guardian]

6.1 Observation

Two million people will be diagnosed with cancer during the next parliament [Cancer Research UK]

6.10.1 Politiques (USA)

Biotech execs, academic leaders make case for NIH funding at White House meeting [Science]

6.7 DMP, Big Data & applis

CancerLinQ LLC and the College of American Pathologists Launch Partnership to Improve Cancer Knowledge Base for Physicians and Patients [ASCO]

Four Lessons In The Adoption Of Machine Learning In Health Care [Health Affairs Blog]

6.8 Communication

Radiology society’s PR message about untreated breast cancer: Sound evidence or scare-mongering? [HealthNewsReview]