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5. Traitements
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5.10 Traitements - Essais
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Draft guideline on multiplicity issues in clinical trials [EMA]
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This
guideline is intended to provide guidance on how to deal with multiple
comparison and control of type I error in the planning and statistical
analysis of clinical trials. From the points to consider document
published in 2002, aspects related with multiplicity issues in safety,
drug-response studies, secondary endpoints, subgroup analysis and
estimation were added or updated, and statistical terms were clarified.
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5.12 Immunothérapies
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5.12.1 Immunothérapies - partenariats
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5.12.2 Immunothérapies - CAR-T
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Making CAR T-Cell Therapy Safer [The Scientist]
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Following
a spate of patient deaths in clinical trials testing modified T cells
for the treatment of cancer, researchers work to reduce the treatment’s
toxicity without sacrificing efficacy.
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5.2 Pharma
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5.2.3 Pharma - économie
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5.3.4 Traitements - AMM (FDA, EMA)
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5.9 AACR
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Aggressive breast cancer grows faster in obese environment [UNC Lineberger]
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For
the study, researchers in the Makowski lab studied a type of breast
cancer known as triple-negative breast cancer. Researchers transplanted
and grew triple negative breast cancer cells from lean laboratory models
into models of obese, lean and formerly obese microenvironments to
observe how tumors grew in these different contexts.
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6. Lutte contre les cancers
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6.1 Observation
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6.10.1 Politiques (USA)
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6.11 Patients
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Cancer patient's family stands to lose £50k under benefit cuts [The Guardian]
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“My
death, on or before Thursday, changes my family’s wellbeing to the tune
of tens of thousands. It is utterly unbelievable.” Alan’s voice
cracked, not just with emotion but the brutal impact of four years of
cancer that started in a tonsil before spreading to his lungs and chest,
delivering a terminal diagnosis in June, 2015.
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6.6 Publications
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