lundi 20 mars 2017

Onco Actu du 20 mars 2017

3.1 Tabac

Poor, minority neighborhoods have more tobacco-selling shops per capita [Reuters]

3.2 Prévention - Obésité

How obesity causes cancer, and may make screening and treatment harder [The Conversation]

3.3 Prévention - Vaccins

First Global Guidance for HPV Vaccination for Cervical Cancer Prevention [ASCO]

4. Dépistage, diagnostic et pronostic

PET scans showing how much oxygen is in a tumour could help monitor the effects of targeted drugs [Cancer Research UK]

5. Traitements

Drug fused to antibody shrinks triple negative breast tumours [Cancer Research UK)

‘Practice changing’ study defines standard of care for elderly glioblastoma patients [Cancer Research UK)

PARG inhibitors: tipping the scales with a new experimental drug [Cancer Research UK]

5.12 Immunothérapies

I-O latecomers Pfizer and Merck KGaA fall further behind rivals with new lung cancer delays [FiercePharma]

5.12.2 Immunothérapies - CAR-T

CAR-T drugs worth up to $649K in childhood leukemia, says U.K. report [FiercePharma]

5.2.3 Pharma - économie

French biotech firm closes in on cancer that killed Steve Jobs [Reuters)

5.3 Traitements - FDA, EMA, NICE...

The FDA chief must not be a proxy for industry [Nature]

5.3.4 Traitements - AMM (FDA, EMA)

New Therapeutic Approved by FDA to Treat Breast Cancer [Cancer Research Catalyst]

FDA Approves New Use for Lenalidomide in Multiple Myeloma [NCI]

5.4 Traitements - Economie

NICE set to reject Janssen’s Darzalex for multiple myeloma [PharmaTimes]

'Unacceptable' plans revealed by NICE that could delay availability of drugs on the NHS in England [Cancer Research UK]

5.9 AACR

Dana-Farber Faculty to present abstracts at 2017 AACR Annual Meeting April 1-5, 2017 in Washington, DC [Dana-Farber]

5.9.1 ASTRO

Combination of radiation and immune checkpoint therapy holds potential for lung cancer [ASTRO]

SBRT offers curative option for lung cancer patients age 80 and older [ASTRO]

Updated Data on SBRT Radiation for NSCLC Lung Cancer Confirm Benefits of ‘One and Done’ Approach [Roswell Park Cancer Institute]

Proton therapy offers new treatment possibility for recurrent lung cancer [ASTRO]

Genetic profile of treatment-resistant lung cancer more variable than previously understood [ASTRO]

Biomarker blood test shows cancer recurrence months before CT scans [ASTRO]

6.10 Politiques

China considers ways to speed up time to market for imported drugs [Reuters]

6.10.1 Politiques (USA)

For scientists, research cuts proposed by Trump are alarming — and deeply personal [STAT]

Trump faces backlash on health-agency cuts [Nature]

Trump’s NIH budget may include reducing overhead payments to universities [Science]

AACR Strongly Opposes the Draconian Cuts to Medical Research Proposed in President Trump’s FY 2018 Budget [AACR]

President’s Budget will Devastate U.S. Research Enterprise [ASCO]

Trump’s budget takes a big bite out of the NIH, with big new fees for biopharma [EndPoints]

Trump NIH Cuts Would Be 'Catastrophic Event,' Says Bush-Era NIH Chief [Forbes]

Statement from ASH President Kenneth C. Anderson, MD, on Administration’s Proposed Cuts to NIH [ASH]

US science agencies face deep cuts in Trump budget [Nature]

6.7 DMP, Big Data & applis

Research paper slams DeepMind/Royal Free NHS Trusts data deal [PharmaTimes]

Google DeepMind's NHS deal under scrutiny [BBC News]

6.9 Controverses

MD Anderson’s Hicks Named Interim President After DePinho Resignation [Xconomy]