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1. Biologie
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Ways of escape [The Darwin Cancer Blog]
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Resistance
to cancer chemotherapy is the consequence of evolutionary resilience – a
four billion year legacy. The surprise is not drug resistance but the
fact that some disseminated and intrinsically lethal cancers are drug
sensitive and curable – the best examples being childhood acute
lymphoblastic leukaemia, testicular cancer and choriocarcinoma.
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3.8 Prévention - Alimentation
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4.7 Dép., diag. & prono. - Col de l'utérus
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5. Traitements
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5.10 Traitements - Essais
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5.12.2 Immunothérapies - CAR-T
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Servier, Pfizer get FDA OK to start US testing of an off-the-shelf CAR-T from Cellectis [EndPoints]
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Cellectis,
though, is out to prove that it can safely treat cancer patients with a
therapy that can be mass manufactured for all patients. By using
off-the-shelf T cells, they have to prove that they can do it without
triggering a dangerous immune response, which has been an issue in the
compassionate use cases followed before. Now this is all being played
out in the clinic for the first time.
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5.2 Pharma
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5.2.3 Pharma - économie
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6.1 Observation
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6.10 Politiques
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6.10.1 Politiques (USA)
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6.11 Patients
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6.9 Controverses
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