vendredi 24 février 2017

Onco Actu du 24 février 2017

1. Biologie

Watching how ‘young’ cells move gives clues on skin cancer spread [Cancer Research UK]

3.8 Prévention - Alimentation

Five-a-day of fruit and veg is good, but '10 is better' [NHS Choices]

Meet the people who eat 10 portions of fruit and vegetables a day [The Guardian]

4. Dépistage, diagnostic et pronostic

Measuring patients' muscles to predict chemotherapy side effects [UNC Linberger]

4.12 Biopsies liquides

FDA’s personalized medicine head leaves for Grail [FierceBiotech]

4.2 Dép., diag. & prono. - Génome

The power — and the fear — of knowing your cancer genome [STAT]

4.5 Dép., diag. & prono. - Colorectal

NICE recommends wider use of tests to detect cancer-causing genetic condition [NICE]

NICE Issues Diagnostics Guidance on Molecular Testing Strategies for Lynch Syndrome in Patients with Colorectal Cancer [ESMO]

5. Traitements

PI3K/mTOR Inhibitors May be Effective Against Some Uterine Sarcomas [AACR]

5.10 Traitements - Essais

Cyclacel AML drug fails phase 3, wiping 30% off stock [FierceBiotech]

Cyclacel Announces Top-Line Results From Pivotal Phase 3 SEAMLESS Study in Elderly Patients With Acute Myeloid Leukemia [Cyclacel]

Cyclacel's leukemia drug for elderly patients fails in key study [Reuters]

5.12.2 Immunothérapies - CAR-T

CAR T Cells More Powerful When Built With CRISPR, MSK Researchers Find [Memorial Sloan Kettering Cancer Center]

5.2 Pharma

Aveo takes baby step forward for once-rejected tivozanib [FierceBiotech]

Novartis receives positive CHMP opinion for Tafinlar® + Mekinist® in BRAF-positive non-small cell lung cancer (NSCLC) patients [Novartis]

CHMP Issues Positive Opinion Recommending DARZALEX® (daratumumab) for Relapsed or Refractory Multiple Myeloma [Genmab]

Genmab outlines a megablockbuster future for itself and J&J as Darzalex gains market traction [EndPoints]

Celgene president, COO Jackie Fouse to make shock departure [FierceBiotech]

5.2.1 Pharma - Partenariats

Incyte turns to Penn for a collaboration on next-gen cancer combos [EndPoints]

5.2.3 Pharma - économie

Big Pharma Quietly Enlists Leading Professors to Justify $1,000-Per-Day Drugs [ProPublica]

5.3 Traitements - FDA, EMA, NICE...

Approving new drugs [Science]

6. Lutte contre les cancers

5 ways to improve care at the end of life [STAT]

6.1 Observation

Apparent inverse relationship between cancer and dementia disappears in new study [Stanford Medicine]

6.7 DMP, Big Data & applis

MD Anderson Cancer Center’s IBM Watson project fails, and so did the journalism related to it [HealthNewsReview]