jeudi 23 février 2017

Onco Actu du 23 février 2017

1. Biologie

Scientists Identify Chain Reaction That Shields Breast Cancer Stem Cells From Chemotherapy [Johns Hopkins]

Conditional Reprogramming: An Interview with Dr. Richard Schlegel on Growing Cancer Cells [NCI]

3.8 Prévention - Alimentation

Fruit and veg: For a longer life eat 10 a day [BBC News]

Forget five a day, eat 10 portions of fruit and veg to cut risk of early death [The Guardian]

4. Dépistage, diagnostic et pronostic

Specialty Physician Groups Publish Guideline to Improve Care for Acute Leukemia Patients [ASH]

4.5 Dép., diag. & prono. - Colorectal

A one-off bowel scope helps prevent bowel cancer, but it’s taking time to reach everyone eligible [Cancer Research UK]

5.12.5 Immunothérapies - Pharma

Argos kidney cancer vax fails phase 3 futility review, future in doubt [FierceBiotech]

Independent Data Monitoring Committee Recommends Discontinuation of the ADAPT Phase 3 Clinical Trial of Rocapuldencel-T in Metastatic Renal Cell Carcinoma for Futility Following Its Planned Interim Data Review [Argos]

Agenus’ lead cancer vaccine flops, investigators read last rites over glioblastoma PhII [EndPoints]

Argos’ PhIII for its personalized cancer vaccine implodes during an interim analysis [EndPoints]

5.2 Pharma

Novartis drug Zykadia receives FDA Priority Review for first-line use in patients with ALK+ metastatic NSCLC [Novartis]

Novartis cancer drug Zykadia gets FDA priority review [Reuters]

5.2.2 Pharma - Fusions & Acquisitions

2016 went out like a lamb in the biopharma M&A world. Will it roar back in 2017? Plus, top 10 deals [EndPoints]

5.2.3 Pharma - économie

Cancer startup PMV Pharma gains impressive $74M B round [FierceBiotech]

Mundipharma to launch Mabthera biosimilar in EU markets [PharmaTimes]

PMV Pharma gets a whopping $74M round to test a new p53 drug in humans [EndPoints]

5.4 Traitements - Economie

Many U.S. cancer patients struggle to afford life-saving medications [Reuters]

6. Lutte contre les cancers

Exercise 'most proven method' to prevent return of breast cancer [NHS Choices]

Exercise linked to better breast cancer outcomes [Reuters]

6.7 DMP, Big Data & applis

CancerLinQ Partners with Premier Radiation Oncology Society [ASCO]