jeudi 2 février 2017

Onco Actu du 2 février 2017

1. Biologie

Online database aims to collect, organize research on cancer mutations [WUSTL]

The biology of cancer cell shape and why it’s important [Cancer Research UK]

2. Etiologie

Poor Metabolic Health Associated With Increased Risk for Colorectal Cancer in Normal-weight Postmenopausal Women [AACR]

3.1.1 Tabac - e-cigs

Australian ban on nicotine e-cigarettes to remain – Expert Reaction [Science Media Centre]

Are E-cigarettes Leading More Kids to Smoke? [NIH Director's Blog]

4. Dépistage, diagnostic et pronostic

Diabetes could be a warning sign of pancreatic cancer [NHS Choices]

4.10 Dép., diag. & prono. - FDA, EMA, NICE,...

HHS Nominee Tom Price Targeted Panel That Urged Fewer Cancer Screenings [NPR]

4.12 Biopsies liquides

MD Anderson and Guardant Health announce partnership to make comprehensive liquid biopsy part of oncology standard of care [MD Anderson]

4.9 Dép., diag. & prono. - Sein

One key detail you’re unlikely to see in news stories about mammography screening guidelines [HealthNewsReview]

5. Traitements

Ovarian cancer drug could target gene fault in brain tumours [Canccer Research UK]

Reprogrammed skin cells shrink brain tumors in mice [Science]

5.10 Traitements - Essais

Adding antiandrogen therapy to radiation therapy improves survival in recurrent prostate cancer [Mass. General Hospital]

Old drug gets new trick for prostate cancer treatment [STAT]

Hormone Blockers Can Prolong Life if Prostate Cancer Recurs [NY Times]

5.12 Immunothérapies

Immunotherapy 2.0 Named Advance of the Year in ASCO’s 12th Annual Cancer Progress Report [ASCO]

5.12.2 Immunothérapies - CAR-T

Another top Genentech exec gets poached, this time taking the helm at CAR-T player Bellicum [EndPoints]

5.2 Pharma

Bristol-Myers Squibb Announces European Patent Office Decision on Sprycel [BMS]

This mysterious $2 billion biotech is revealing the secrets behind its new drugs and vaccines [Science]

Pfizer Needs to Keep Dealing [Bloomberg]

Competition stalls Roche margin growth; drugmaker commits to diabetes unit [Reuters]

5.2.3 Pharma - économie

Big Pharma promised Trump new American jobs for tax cuts and deregulation. But the vow comes after a 5-year purge [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

Trump Pledges to Gut FDA: Which Regulations Need to Go? [RAPS]

What if the FDA is eliminated? [Health Business Blog]

Lobbyists, lawmakers slam Trump’s plan to slash regulation [FierceBiotech]

Withdrawal of the Application for a Change to the Marketing Authorisation for Denosumab [ESMO]

5.3.4 Traitements - AMM (FDA, EMA)

EU clears Merck’s Keytruda for un-treated lung cancer [PharmaTimes]

5.4 Traitements - Economie

Trump has big plans to fix drug prices. Here’s your reality check [STAT]

6. Lutte contre les cancers

Let’s talk about cancer: the Manchester project that aims to save lives [The Guardian]

6.10 Politiques

The time is ripe to reform the World Health Organization [Nature]

6.10.1 Politiques (USA)

Statement from ASH, AACR, AACI, ASTRO, ASPHO, and LUNGevity Foundation on the Administration’s Executive Order on Immigration [AACR]

On 22 April, empiricists around the country will march for science [Science]

President Trump, the Cancer Moonshot and the new war on drug pricing [The Institute of Cancer Research]

Scientists protest immigration ban with boycotts of journals, conferences [STAT]

6.11 Patients

Young women with breast cancer learn to celebrate life — and say goodbye [STAT]

6.6 Publications

Richard Smith: Time for pharmaceutical companies to help improve the publishing of science [BMJ Blogs]

6.7 DMP, Big Data & applis

Moving Patient Data Is Messy, But Blockchain Is Here to Help [Wired]