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1. Biologie
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3.1 Tabac
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3.2 Prévention - Obésité
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4.11 Dép., diag. & prono. - Ovaire
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4.9 Dép., diag. & prono. - Sein
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5. Traitements
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5.12.2 Immunothérapies - CAR-T
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5.3 Traitements - FDA, EMA, NICE...
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5.4 Traitements - Economie
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Venetoclax for treating chronic lymphocytic leukaemia [NICE]
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The
committee concluded that people enrolled in the venetoclax clinical
trials were likely to have a lower burden of disease than the people for
whom venetoclax would be an option in England, and that the treatment
benefit for these people was therefore uncertain.
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NICE rejects AbbVie’s leukaemia drug [Pharmafile]
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NICE
has rejected AbbVie Venclyxto (venetoclax) for the treatment of chronic
lymphocytic leukmaemia, on various grounds but primarily focusing upon
the evidence base for the drug. Pricing was also an issue for the drug,
exceeding the £30,000 per QALY limit.
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5.5 ASCO
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6. Lutte contre les cancers
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6.7 DMP, Big Data & applis
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6.9 Controverses
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Stop Freaking Out About CRISPR! (Except For One Thing) [Forbes]
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Editas’
license to its patents grants it exclusivity for using CRISPR only on
the diseases where it is actually developing treatments. That leaves
plenty of room for other companies, and plenty of incentive for the
patent owners to grant out other licenses. All this drama may be over
single-digit royalty rates.
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Broad Institute wins bitter battle over CRISPR patents [Nature]
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One
of the inventors on that patent, molecular biologist Jennifer Doudna of
the University of California in Berkeley, likened the situation to
licensing permission to someone who wants to use green tennis balls.
"They will have a patent on the green tennis balls," she said, referring
to the Broad patents. "We will have a patent on all tennis balls."
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