lundi 23 janvier 2017

Onco Actu du 23 janvier 2017

1. Biologie

John Arnold Made a Fortune at Enron. Now He’s Declared War on Bad Science [Wired]

New insight into origin of stomach cancer [WUSTL]

Pancreatic tumors rely on signals from surrounding cells [Salk]

Mayo researchers identify mechanism of oncogene action in lung cancer [Mayo Clinic]

2.11 Etiologie - Alimentation

Browned toast and potatoes are 'potential cancer risk', say food scientists [BBC News]

UK scientists give cancer risk warning on overdone chips, toast [Reuters]

3.1 Tabac

Stop smoking services may boost mental health of people with depression [Cancer Research UK]

4. Dépistage, diagnostic et pronostic

Next Generation: Mobile Microscope Detects DNA Sequences [The Scientist]

4.1 Dép., diag. & prono. - Prostate

MRI scans could spare 25% of men from prostate biopsies [NHS Choices]

5.12 Immunothérapies

Opdivo Shows Appetite for Gastric Cancer [OBR Blog]

Scrambled DNA inside tumours might hinder cancer immunotherapy [Cancer Research UK]

5.12.2 Immunothérapies - CAR-T

Cellectis Studies Safety in New CAR Architecture Controlling CAR T-Cell Functions [Cellectis]

5.12.5 Immunothérapies - Pharma

Bristol-Myers Squibb, Where Art Thou? Not in First-Line Lung Cancer Immunotherapy, Sadly [The Street]

Bristol's Opdivo Dependence Now Looks Dicey [Bloomberg]

Merck, Bristol-Myers agree to settle Keytruda patent suit [Reuters]

Bristol-Myers Squibb and Ono Pharmaceutical Company Enter Settlement and License Agreement with Merck to Resolve PD-1 Antibody Patent Litigation [BMS]

5.2 Pharma

Regorafenib from Bayer Granted Priority Review in Japan for the Second-Line Treatment of Liver Cancer [Bayer]

5.3 Traitements - FDA, EMA, NICE...

22 Case Studies Where Phase 2 and 3 Results Diverge: New FDA Report [RAPS]

22 Case Studies Where Phase 2 and Phase 3 Trials had Divergent Results [FDA]

AACR Applauds Appointment of Richard Pazdur, MD, as Director of the FDA Oncology Center of Excellence [AACR]

5.3.4 Traitements - AMM (FDA, EMA)

Imbruvica gets US nod for marginal zone lymphoma [Pharma Times]

6. Lutte contre les cancers

Bernard Merkel: Should patients really be at the centre of healthcare? [BMJ Blogs]

Cancer patients with depression have resources [Reuters]

6.1 Observation

Cervical Cancer Taking Deadlier Toll in U.S. Than Had Been Thought [NY Times]

6.11 Patients

The chemo’s too much, but getting on a clinical trial is gruelling enough [The Guardian]

6.2 Implants mammaires

PIP breast implants: French court tells TUV to pay damages [BBC News]