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3.1 Tabac
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U.S. Will Ban Smoking in Public Housing Nationwide [NY Times]
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The
nationwide ban will have its greatest impact in New York, where the New
York City Housing Authority — whose 178,000 apartments and more than
400,000 residents make it the largest public housing agency in the
United States, has lagged behind many of its counterparts in adopting
smoke-free policies.
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3.1.1 Tabac - e-cigs
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5. Traitements
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5.12 Immunothérapies
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5.12.2 Immunothérapies - CAR-T
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Deaths in Immune-Therapy Trials Haunt the Experimental Cancer Treatment [MIT Technology Review]
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The
problem is these engineered T cells have the potential to stimulate the
immune system too much. This can lead to cytokine release syndrome, one
of the well-known side effects of immune therapies like CAR-T. But the
five patients in the Juno trial died from a different condition,
cerebral edema, or swelling of the brain. In other trials of CAR-T
therapies, neurological side effects have occurred but were mostly
short-lived.
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Triple meeting – Bluebird upstages its Ash rivals [EP Vantage]
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The
data are early but striking: seven of nine late-line, post-transplant,
multiple myeloma patients have gone into remission, with no serious
toxicities. The result upstages other anti-BCMA CARs in the clinic,
including one linked to Novartis, and sets a new benchmark for Kite,
Juno and Cellectis’s preclinical projects.
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5.2 Pharma
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5.3 Traitements - FDA, EMA, NICE...
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5.8 ASH
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58th ASH Annual Meeting to Celebrate Major Advances in Hematology Research [ASH]
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The
2016 ASH Annual Meeting will feature nearly 5,000 scientific abstract
presentations in malignant and non-malignant blood diseases – from
cutting-edge advances in genome editing and discoveries about biological
processes of the blood to practice-changing breakthroughs in
immunotherapies and innovative treatment combinations.
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5.9.4 ENA
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How highs and lows in testosterone levels ‘shock’ prostate cancer cells to death [ECCO]
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Traditionally,
treatments for prostate cancer have involved lowering the levels of the
male hormone (or androgen) testosterone using drugs called luteinising
hormone-releasing hormone (LHRH) agonists, as it was thought that
androgens stimulate the cancer cells to grow. However, Prof Denmeade
says there is no evidence that testosterone promotes cancer.
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6. Lutte contre les cancers
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6.1 Observation
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6.10 Politiques
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6.10.1 Politiques (USA)
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House approves the 21st Century Cures Act, sending landmark bill to Senate [STAT]
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The
Cures Act includes numerous provisions that set the stage for the
faster approval of prescription drugs and medical devices. Although
proponents claim these new measures will not lower safety standards,
numerous critics, including some former Food and Drug Administration
officials and national consumer groups, disagree.
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Why Patients Support the 21st Century Cures Act [Forbes]
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Why
I’m writing is that I’ve read some stories suggesting that “Cures” is
all about perks for pharmaceutical companies, and that industry-funded
advocacy groups are parading patients, like puppets, before legislators
to promote the bill.
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6.11 Patients
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6.3 Associations/Fondations
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6.6 Publications
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How to keep up with the scientific literature [Science]
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Beginning
a new research project or writing a grant application can be good
opportunities for extensive literature searches, but carving out time to
keep abreast of newly published papers on a regular basis is often
challenging. The task is all the more daunting today, with the already
vast literature continuing to grow at head-spinning speed.
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6.7 DMP, Big Data & applis
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