mercredi 14 décembre 2016

Onco Actu du 14 décembre 2016

1. Biologie

Mystery molecule is a key to inhibiting colon cancer [St. Jude Children’s Research Hospital]

Piecing together breast cancers’ immune cell composition [Cancer Research UK]

Single Tumor Cells Reveal Clues to Biology of Multiple Myeloma [NCI]

3.1 Tabac

Study Finds No Safe Level of Smoking [NIH's Director Blog]

4.12 Biopsies liquides

Blood test could provide cheaper, better way for doctors to manage lung cancer [Stanford Medicine]

4.2 Dép., diag. & prono. - Génome

Personal-genome cancer-risk profile may not inspire lifestyle changes [Reuters]

5. Traitements

New X-ray technique could improve bomb detection and breast cancer treatment [ESPRC]

Rub-on cream for skin cancer nearly as effective as surgery, five year trial shows [The Telegraph]

5.12 Immunothérapies

Immunotherapy drug extends lives of advanced lung cancer patients [Cancer Research UK]

Algorithms compete to predict recipe for cancer vaccine [Nature]

5.12.1 Immunothérapies - partenariats

Pfizer joins rush to cancer vaccine R&D, backing startup Ignite [FierceBiotech]

Kite Pharma and Vitruvian Networks Enter Strategic Partnership to Develop Best-In-Class Logistics and Data Analytics Software for Engineered T-cell Therapies at Commercial Scale [Kite]

5.2.3 Pharma - économie

Not Fun Reading [In the Pipeline]

Measuring the return from pharmaceutical innovation 2016 [Deloittte]

Big Pharma’s woeful numbers on drug R&D just got even worse [EndPoints]

As drug approvals dive in 2016, returns on R&D deteriorate [Reuters]

5.3 Traitements - FDA, EMA, NICE...

EMA hosts workshop on adaptive pathways [EMA]

The President Signs 21st Century Cures into Law; Highlights of Drug and Biologic Related Provisions (Part One) [FDA Law Blog]

5.3.4 Traitements - AMM (FDA, EMA)

European Commission Grants Marketing Authorization for Arzerra® (ofatumumab) in combination with Fludarabine and Cyclophosphamide in Relapsed CLL [Genmab]

5.4 Traitements - Economie

We Need To Tame The Price Of New Cancer Drugs [Forbes]


SABCS 2016: The Search for an Effective and Safe PI3K-Inhibitor [Cancer Research Catalyst]

6.10.1 Politiques (USA)

21st Century Cures Act: Making Progress on Shared Goals for Patients [FDA Voice]

The FDA Should Approve Drugs Based on Evidence, Not Emotions [Slate]

The 21st Century Cures Act — A View from the NIH [NEJM]

It’s the law: Obama signs widely popular 21st Century Cures Act [EndPoints]