lundi 12 décembre 2016

Onco Actu du 12 décembre 2016

3.1 Tabac

FDA warns four companies for labeling flavored cigarettes as cigars [Reuters]

3.1.1 Tabac - e-cigs

The Great British vape off [Cancer Research UK]

3.6 Prévention - Activité physique

Better aerobic fitness may reduce men’s risk of cancer death [Reuters]

5.12 Immunothérapies

AstraZeneca's immunotherapy enters U.S. approval process [Reuters]

5.12.1 Immunothérapies - partenariats

Provectus, POETIC to Study Immunotherapy Candidate for Pediatric Cancers [GEN]

5.2 Pharma

Bioinvent back to drawing board as it pulls trial of lead drug for myeloma [FierceBiotech]

Your attention, please: AstraZeneca asks for a moment of rapt silence, for a BLA acceptance? [EndPoints]

5.3 Traitements - FDA, EMA, NICE...

EMA Revises Clinical Data Publication Guidance, Updates on Program [RAPS]

5.3.4 Traitements - AMM (FDA, EMA)

FDA Approves New Use for Daratumumab in Multiple Myeloma [NCI]

5.4 Traitements - Economie

Pay-for-performance drug pricing: Drugmakers asked to eat costs when products don't deliver [Modern Healthcare]


Naturally occurring symptoms may be mistaken for tamoxifen side-effects [Cancer Rersearch UK]

5.7.1 SABCS-communiqués

Genomic Health Announces Results from Multiple Oncotype DX® Studies, Reinforcing its Impact in Delivering Precision Medicine to Breast Cancer Patients Around the World [Genomic Health]

Image-guided biopsy identifies patients who achieve pathologic complete response after neoadjuvant therapy [MD Anderson Cancer Center]

Seattle Genetics Highlights Phase 1 Data for Novel Antibody-Drug Conjugate SGN-LIV1A in Patients with Metastatic Breast Cancer at San Antonio Breast Cancer Symposium [Seattle Genetics]

The EndoPredict® Test Significantly Outperforms the First-Generation Test in Predicting the Risk of Node-Negative and Node-Positive Breast Cancer Recurrence [Myriad]

Novartis LEE011 (ribociclib) plus letrozole analyses show superior PFS across broad spectrum of patients in first-line HR+/HER2- advanced breast cancer versus letrozole [Novartis]


Scalp-cooling System Reduced Hair Loss in Many Breast Cancer Patients Receiving Chemotherapy [AACR]

Women Experiencing Menopausal Symptoms Less Likely to Adhere to Medication in Breast Cancer Prevention Trial [AACR]

Aromatase Inhibitors Were Associated With Reduced Endothelial Function in Postmenopausal Breast Cancer Patients [AACR]

IBM Watson for Oncology Platform Shows High Degree of Concordance with Physician Recommendations [AACR]

Breast Cancer Mortality Rates Decline in Many Countries [AACR]

6.1 Observation

Lonely women are more likely to die from returning breast cancer - new research [The Telegraph]

6.10.1 Politiques (USA)

ASCO Applauds Congress for Funding Cures, Expresses Concerns with Underlying Stagnant NIH Budget [ASCO]

The Politics of the 21st Century Cures Act [In the Pipeline]

Being an Acting Director, NCI’s Lowy Isn’t Required to Submit Resignation [The Cancer Letter]

NIH Director Francis Collins says he would remain in post under Trump [STAT]

6.11 Patients

AA Gill: Final article describes cancer treatment [BBC News]

AA Gill said NHS could not give him new cancer treatment [The Guardian]

6.4 Médico-éco

DePinho Accepts Responsibility As MD Anderson’s Losses Grow [The Cancer Letter]

6.5 Médecines alternatives

Can the mind really heal the body? The false narrative of placebo “healing” revisited [Science-Based Medicine]

6.9 Controverses

The Cancer Lottery [MIT Technology Review]