vendredi 4 novembre 2016

Onco Actu du 4 novembre 2016

2. Etiologie

Seven substances added to 14th Report on Carcinogens [NIH]

Seven agents, including HIV, added to U.S. list of carcinogens [Reuters]

2.9 Etiologie - Tabac

Scientists reveal genetic ‘signatures’ left by cigarette smoke [Cancer Research UK]

DNA study lays bare devastating damage caused by smoking [The Guardian]

Smoking a pack a day causes 150 mutations in every lung cell, research shows [Reuters]

3.1 Tabac

Exclusive - Tobacco treaty leaders propose barring delegates linked to state firms [Reuters]

3.2 Prévention - Obésité

Childhood obesity levels hit ‘devastating record high’ [Cancer Research UK]

Child obesity rising again, NHS report reveals [The Guardian]

5. Traitements

Ribociclib for HR-Positive Breast Cancer [Now@NEJM]

Missile tracking [The Economist]

5.10 Traitements - Essais

What clinical trial results? Now you can see who isn’t sharing their findings [STAT]

Sanofi, Novartis, NCI, Ranbaxy top missing data list as Shire most transparent [FierceBiotech]

Tracker flags up failures to report clinical trials [Nature]

The TrialsTracker: Automated ongoing monitoring of failure to share clinical trial results by all major companies and research institutions [F1000 Research]

5.12.2 Immunothérapies - CAR-T

Celyad chief blasts Cellectis’ CEO Choulika, claiming he lied about CAR-T patent [EndPoints]

5.2.1 Pharma - Partenariats

Stand Up To Cancer Announces SU2C Catalyst™ Collaboration with Genentech to Support New Research on Cancer Treatments and Therapies [AACR]

5.2.3 Pharma - économie

Boehringer backs $20M round in ADC cancer player [FierceBiotech]

5.4 Traitements - Economie

Blood cancer sufferers to receive early access to BMS' Opdivo [Pharmafile]

5.8 ASH

Shaky early results on novel drugs send biotech stocks crashing [STAT]

The losers are piling up after today’s big ASH abstract drop [EndPoints]

5.8.1 ASH - Communiqués

Juno Therapeutics to Highlight CAR T Advances in B-cell Malignancies at ASH 2016 [Juno]

ASH 2016: Janssen to Present 43 Abstracts with Data on Ibrutinib, Daratumumab and Other Compounds Showing Treatment Advances in Malignant and Non-Malignant Hematologic Conditions [Janssen]

Seattle Genetics Announces ASH 2016 Abstracts Highlighting Company’s Expanding Global Leadership in the Development of Innovative Antibody-Drug Conjugates [Seattle Genetics]

ImmunoGen Announces Preclinical Data Presentations for Two ADCs With Novel IGN Payloads at Upcoming 58th ASH Annual Meeting [ImmunoGen]

Bristol-Myers Squibb to Present New Data at the 58th Annual Meeting & Exposition of the American Society of Hematology Demonstrating Research Advancements in Immuno-Oncology and Across Multiple Blood Cancers [BMS]

AbbVie to Showcase Growing Oncology Portfolio and Commitment to Treating Blood Cancers at the 2016 American Society of Hematology Annual Meeting [AbbVie]

Kite Pharma to Present KTE-C19 Data from Interim Analysis of the ZUMA-1 Pivotal Trial in Patients with Chemorefractory Primary Mediastinal B-Cell Lymphoma (PMBCL) and Transformed Follicular Lymphoma (TFL) at the 2016 American Society Hematology Annual Meeting [Kite]

Takeda to Present Broad Range of Clinical Data During 58th American Society of Hematology Annual Meeting [Takeda]

Roche showcases new clinical data across a variety of blood diseases at American Society of Hematology 2016 Annual Meeting [Roche]

6. Lutte contre les cancers

We need better treatments for childhood cancer, with fewer side effects [The Conversation]

6.11 Patients

Living With Cancer: A Shortage of Oncologists [NY Times]

6.6 Publications

Hey scientists, how much of your publication success is due to dumb luck? [Science]

Authors retract third cancer paper for missing original data [Retraction Watch]

6.7 DMP, Big Data & applis

Will Big Data Cure Cancer? [Fortune]

Flatiron, Foundation Med Link Records of 20,000 Cancer Patients [Xconomy]