jeudi 17 novembre 2016

Onco Actu du 17 novembre 2016

3.1 Tabac

Cuts to public health funding are crippling Stop Smoking Services [Cancer Research UK]

5. Traitements

Pop-up pill could stay in stomach to release drugs for days [STAT]

Modified virus could turn immune system on liver cancer [Cancer Research UK]

Direct Small-Molecule Inhibitors of KRAS [ESMO]

The Drug Development Paradigm in Oncology: A Workshop [National Academies]

5.12.1 Immunothérapies - partenariats

Merck pairs PD-1 powerhouse Keytruda with Genexine vax to fight HPV-based cancers [FiercePharma]

Bristol-Myers, Enterome pen microbiome I/O research pact [FierceBiotech]

Bristol-Myers Squibb and Enterome Announce Immuno-Oncology Collaboration Focused on Microbiome-Derived Biomarkers, Drug Targets and Bioactive Molecules [BMS]

5.2 Pharma

Amgen, Allergan step up to challenge Roche's Avastin with FDA biosim filing [FiercePharma]

Led by Former Lilly Exec, Apexian Out to Tackle Pancreatic Cancer [Xconomy]

ARIAD Announces Data Presentations at the World Conference on Lung Cancer [Ariad]

Bristol-Myers Squibb Presents New Data at IASLC 17th World Conference on Lung Cancer Underscoring Progress and Leadership in Broad Lung Development Program [BMS]

Gilead racks up another R&D setback as myelofibrosis drug flounders in PhIII [EndPoints]

5.2.3 Pharma - économie

How to Lower Drug Prices, Improve Care, and Save Pharma [Xconomy]

5.4 Traitements - Economie

NICE approves three quarters of CDF group 1 drugs for routine use [NICE]

The AMA on value-based drug pricing [Healthcare Economist]

NICE says pancreatic cancer treatment considered not cost effective for routine NHS use [NICE]

Breast cancer drug approved for NHS use after price cut [The Guardian]

Japan sets 50 percent price cut for Bristol Myers' Opdivo cancer drug [Reuters]

Roche, Bristol-Myers cut cancer drug prices to win UK approval [Reuters]

America's drug problem [Nature Biotechnology]

5.5 ASCO

ASCO’s TAPUR Study Now Has More Than One Hundred Participants Receiving Treatment Drugs and Twenty-Five New Clinical Trial Sites [ASCO]

6. Lutte contre les cancers

DIY breast reconstruction: Device lets women do part of the surgical prep at home [STAT]

NHS England has at last listened to calls to focus on radiotherapy [The Telegraph]

6.1 Observation

Black African women almost twice as likely to be diagnosed with late stage breast cancer compared to white women [Cancer Research UK]

6.7 DMP, Big Data & applis

Neal Patterson’s Remarks from CHC [Cerner]