Onco Actu du 18 octobre 2016

	2.7 Etiologie - Obésité
One More Reason to Stay Trim: Reduce Your Liver Cancer Risk [AACR] “While some other well-described risk factors, such as hepatitis B virus or hepatitis C virus, are associated with increased risks of liver cancer, these factors are much less common than are obesity and diabetes.”
	4. Dépistage, diagnostic et pronostic
LLNL scientists develop a new method to measure radiation dose in cancer patients [LLNL] Lawrence Livermore National Laboratory (LLNL) scientists and collaborators have developed a new technique to measure radiation dose levels using gene expression analysis of whole blood from cancer patients receiving targeted radiation therapy.
	4.2 Dép., diag. & prono. - Génome
Veritas Genetics Lands $30M for $1,000 Genome Sequencing [Xconomy] Co-founded by Harvard Medical School professor George Church in 2014, the company has raised $42 million in venture money so far.
	5.4 Traitements - Economie
‘Fast track’ cost effective treatments for patients following NICE changes [European Pharmaceutical Review] Proposed changes to the way the National Institute for Health and Care Excellence (NICE) appraises new treatments could see patients benefiting from the most cost effective treatments nearly three months faster than is currently the case.
Drug maker fined for shorting supplies of cancer drugs in order to raise prices [STAT] A key issue is that Aspen is the only supplier of these particular types of cancer treatments in the Italian market, underscoring that authorities believe the company abused its position.
HHS is urged to allow a drug maker to export cheap versions of pricey cancer med [STAT] In a Oct. 17 letter to the US Department of Health and Human Services, the groups argue that the company, Biolyse, should be allowed to sell a version of the Xtandi prostate cancer treatment to low- and middle-income countries because federally funded research was used to create the drug.
	6. Lutte contre les cancers
A new era for pancreatic cancer: The Dream Team [Cancer Research UK] Professor Gerard Evan is a leading cancer genetics expert at the University of Cambridge, and a co-leader of this Dream Team. We caught up with him to gather his thoughts on working with a group of the world’s best cancer scientists on one of the toughest cancers to beat.
	6.10 Politiques
Cancer targets may delay diagnosis of other conditions, say doctors leaders [BMA] It also create perverse care pathways as clinical commissioining groups and trusts focus solely on hitting the cancer-referral targets but patients who are found not to have cancer are just sent back to their GP without any clarity about what is actually the cause of their symptoms.
	6.10.1 Politiques (USA)
Cancer Moonshot Task Force and Vice President Detail Necessary Next Steps to Accelerate Cancer Research and Prevention [ACS] Advocacy affiliate calls on Congress and state lawmakers to provide necessary funding and take swift action to act to begin implementing recommendations.
Here are 3 big projects the White House cancer moonshot is pursuing [STAT] Major themes include harnessing big data, sharing research among scientists, and expanding preventive measures like the HPV vaccine and colorectal cancer screening. Some of these efforts will be run by the government; others are being led by the private sector.
FACT SHEET: Vice President Biden Delivers Cancer Moonshot Report, Announces Public and Private Sector Actions to Advance Cancer Moonshot Goals [White House] The new actions and public-private partnerships announced today are just some of the over 70 commitments made this year as a result of the Cancer Moonshot.
White House To Announce Big Push For Cancer Blood Tests [Forbes] The dream is that cancer will be able to be detected with a blood test, and that doctors will use genetic information to pick the perfect drug to treat it, too. But that dream is proving difficult to realize.
Biden’s moonshot cancer plan calls for more data sharing [Science] Although cancer researchers welcome the two moonshot reports, Congress now needs to come up with new funding to carry out Biden’s vision, says Jon Retzlaff, managing director of science policy and government affairs for the American Association for Cancer Research in Philadelphia, Pennsylvania.
Cancer Moonshot program is 'close to gigantic progress', Joe Biden says [The Guardian] “I’m going to devote the rest of my life to working on this, and I think we’re perilously close to making some gigantic progress,” Biden told reporters.
Report of the Cancer Moonshot Task Force: Executive Summary [Medium] This report presents the Task Force’s Implementation Plans for accelerating progress, including actions launched under the Cancer Moonshot this year, as well as longer-term plans for continuing momentum into the future.
The Best—and Worst—Things About Joe Biden’s Cancer Moonshot [MIT Technology Review] Its five core goals—from encouraging new scientific breakthroughs to improving patient access and care—are far-reaching but often vague.
VP Biden to report on Cancer Moonshot progress [Reuters] The White House is still seeking about $700 million from Congress for the project. With Democratic President Barack Obama leaving office in January, it is also unclear how much of the initiative will continue under a new administration.
	6.11 Patients
A cancer patient and pathologist — brought together by Twitter — strike up an unlikely connection [STAT] It was a privilege to go the lab with Michael and look at lung cancer cells under the microscope and hold an actual lung. I’m a strong advocate for patients as partners in their own care. I feel that the more we know about our disease, the better we are able to make good choices.
Insecurity, guilt and stigma: The reality of going back to work after breast cancer [The Telegraph] My biggest piece of advice for anyone going back to work after cancer is: make sure you build in time for yourself. Have a counselling session if you feel you need it. Go home a little early if you're exhausted at first. Allow yourself the time to settle back in - that doesn't mean you're not capable, just readjusting.
	6.5 Médecines alternatives
Dr. Richard Rawlins Reveals the Real Secrets of Alternative Medicine [Science-Based Medicine] Rawlins advocates a “kinder, gentler” evidence-based medicine that appreciates human values and condones the use of placebo medicine but only with scrupulous honesty and fully informed consent. There is a wealth of good information here, fully supported by endnotes.
	6.6 Publications
Richard Lehman’s journal review—17 October 2016 [BMJ] The NEJM is meant to be the world’s leading generalist journal, not the Annals of Expensive Oncology.
	6.7 DMP, Big Data & applis
IBM Is Counting on Its Bet on Watson, and Paying Big Money for It [NY Times] The new genomics service, IBM executives say, is one step in the company’s march to build a so-called ecosystem of corporate partners and software developers that use Watson technology.
Thousands More Patients Will Soon Be Able to Use IBM's Watson to Fight Cancer [Fortune] Under the new service, doctors would send Quest a patient’s tissue sample so that it can be genetically sequenced. This genomic information would then be fed to Watson, using its supercomputing powers and Sloan Kettering’s oncology precision medicine database to sift through the latest cancer research and drug trials.